Status: Bibliographieeintrag
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| Verfasst von: | Jarczok, Marc N. [VerfasserIn]  |
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| | Koenig, Julian [VerfasserIn] |
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| | Wittling, Ralf Arne [VerfasserIn] |
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| | Fischer, Joachim E. [VerfasserIn] |
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| | Thayer, Julian F. [VerfasserIn] |
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| Titel: | First evaluation of an index of low vagally-mediated heart rate variability as a marker of health risks in human adults |
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| Titelzusatz: | proof of concept |
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| Verf.angabe: | Marc N. Jarczok, Julian Koenig, Arne Wittling, Joachim E. Fischer, and Julian F. Thayer |
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| E-Jahr: | 2019 |
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| Jahr: | 11 November 2019 |
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| Umfang: | 12 S. |
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| Fussnoten: | Gesehen am 14.04.2020 |
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| Titel Quelle: | Enthalten in: Journal of Clinical Medicine |
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| Ort Quelle: | Basel : MDPI, 2012 |
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| Jahr Quelle: | 2019 |
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| Band/Heft Quelle: | 8(2019,11) Artikel-Nummer 1940, 12 Seiten |
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| ISSN Quelle: | 2077-0383 |
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| Abstract: | Multiple studies have demonstrated low vagally-mediated heart rate variability (HRV) being associated with a range of risk factors for heart disease and stroke, including inflammation, hyperglycemia, hyperlipidemia, and hypertension. Yet, no cut point exists that indicates elevated risk. In the present study we sought to identify a cut point-value for HRV that is associated with elevated risk across a range of known risk factors. Methods: A total of 9550 working adults from 19 study sites took part in a health assessment that included measures of inflammation, hyperglycemia, hyperlipidemia, and hypertension and vagally-mediated HRV (Root mean square of successive differences between normal heartbeats (RMSSD)). Multiple age and sex adjusted logistic regressions were calculated per risk factor (normal versus clinical range), with RMSSD being entered in binary at different cut points ranging from 15-39 msec with a 2 msec increment. Results: For daytime RMSSD, values below 25 +/- 4 indicated elevated risk (odds ratios (OR) 1.5-3.5 across risk factors). For nighttime RMSSD, values below 29 +/- 4 indicated elevated risk (OR 1.2-2.0). Conclusion: These results provide the first evidence that a single value of RMSSD may be associated with elevated risk across a range of established cardiovascular risk factors and may present an easy to assess novel marker of cardiovascular risk. |
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| DOI: | doi:10.3390/jcm8111940 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/jcm8111940 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2077-0383/8/11/1940 |
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| | DOI: https://doi.org/10.3390/jcm8111940 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | age |
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| | cardiovascular-disease |
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| | cvd |
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| | dependence |
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| | glycemic status |
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| | heart rate variability |
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| | inflammation |
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| | link |
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| | mortality |
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| | novel risk factor |
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| | overnight urinary norepinephrine |
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| | prevention |
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| | risk stratification |
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| | values |
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| K10plus-PPN: | 1694431606 |
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| Verknüpfungen: | → Zeitschrift |
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First evaluation of an index of low vagally-mediated heart rate variability as a marker of health risks in human adults / Jarczok, Marc N. [VerfasserIn]; 11 November 2019 (Online-Ressource)
68563841
