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Status: Bibliographieeintrag

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Verfasst von:Michelini, Giorgia [VerfasserIn]   i
 Kitsune, Viryanaga [VerfasserIn]   i
 Vainieri, Isabella [VerfasserIn]   i
 Hosang, Georgina M. [VerfasserIn]   i
 Brandeis, Daniel [VerfasserIn]   i
 Asherson, Philip [VerfasserIn]   i
 Kuntsi, Jonna [VerfasserIn]   i
Titel:Shared and disorder-specific event-related brain oscillatory markers of attentional dysfunction in ADHD and bipolar disorder
Verf.angabe:Giorgia Michelini, Viryanaga Kitsune, Isabella Vainieri, Georgina M. Hosang, Daniel Brandeis, Philip Asherson, Jonna Kuntsi
E-Jahr:2018
Jahr:7 February 2018
Umfang:18 S.
Fussnoten:Gesehen am 15.04.2020
Titel Quelle:Enthalten in: Brain topography
Ort Quelle:Dordrecht [u.a.] : Springer Science + Business Media B.V, 1988
Jahr Quelle:2018
Band/Heft Quelle:31(2018), 4, Seite 672-689
ISSN Quelle:1573-6792
Abstract:Attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) often present with overlapping symptoms and cognitive impairments, such as increased fluctuations in attentional performance measured by increased reaction-time variability (RTV). We previously provided initial evidence of shared and distinct event-related potential (ERP) impairments in ADHD and BD in a direct electrophysiological comparison, but no study to date has compared neural mechanisms underlying attentional impairments with finer-grained brain oscillatory markers. Here, we aimed to compare the neural underpinnings of impaired attentional processes in ADHD and BD, by examining event-related brain oscillations during a reaction-time task under slow-unrewarded baseline and fast-incentive conditions. We measured cognitive performance, ERPs and brain-oscillatory modulations of power and phase variability in 20 women with ADHD, 20 women with BD (currently euthymic) and 20 control women. Compared to controls, both ADHD and BD groups showed increased RTV in the baseline condition and increased RTV, theta phase variability and lower contingent negative variation in the fast-incentive condition. Unlike controls, neither clinical group showed an improvement from the slow-unrewarded baseline to the fast-incentive condition in attentional P3 amplitude or alpha power suppression. Most impairments did not differ between the disorders, as only an adjustment in beta suppression between conditions (lower in the ADHD group) distinguished between the clinical groups. These findings suggest shared impairments in women with ADHD and BD in cognitive and neural variability, preparatory activity and inability to adjust attention allocation and activation. These overlapping impairments may represent shared neurobiological mechanisms of attentional dysfunction in ADHD and BD, and potentially underlie common symptoms in both disorders.
DOI:doi:10.1007/s10548-018-0625-z
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1007/s10548-018-0625-z
 DOI: https://doi.org/10.1007/s10548-018-0625-z
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:ADHD
 Adult
 Adults
 Attention
 Attention Deficit Disorder with Hyperactivity
 Bipolar disorder
 Bipolar Disorder
 Brain
 Brain oscillations
 Cognitive Dysfunction
 Contingent Negative Variation
 EEG
 Event-related potentials
 Evoked Potentials
 Female
 Humans
 Male
 Middle Aged
 Neuropsychological Tests
 Reaction Time
 Young Adult
K10plus-PPN:1694597385
Verknüpfungen:→ Zeitschrift

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