Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa

• Verfasst von: Mogeni, Polycarp [VerfasserIn]
• Verfasst von: Vandormael, Alain [VerfasserIn]
• Verfasst von: Cuadros, Diego [VerfasserIn]
• Verfasst von: Appleton, Christopher [VerfasserIn]
• Verfasst von: Tanser, Frank [VerfasserIn]
• Titel: Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa
• Verf.angabe: Polycarp Mogeni, Alain Vandormael, Diego Cuadros, Christopher Appleton, Frank Tanser
• E-Jahr: 2020
• Jahr: [2020]
• Umfang: ? S.
• Teil: volume:9
• Teil: year:2020
• Teil: extent:?
• Fussnoten: Gesehen am 21.04.2020
• Titel Quelle: Enthalten in: eLife
• Ort Quelle: Cambridge : eLife Sciences Publications, 2012
• Jahr Quelle: 2020
• Band/Heft Quelle: 9(2020) Artikel-Nummer e54012
• ISSN Quelle: 2050-084X
• DOI: doi:10.7554/eLife.54012
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: piped water coverage
• Sach-SW: primary school children
• Sach-SW: re-infection
• Sach-SW: S. haematobium
• Sach-SW: South Africa
• K10plus-PPN: 1695266676

Abstract

Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected members of this nested cohort (N = 333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increase in piped water coverage was associated with 4.4% decline in intensity of re-infection (incidence rate ratio = 0.96, 95% CI: 0.93-0.98, p=0.004) among the treated children. We therefore provide further compelling evidence in support of the scaleup of piped water as an effective control strategy against Schistosoma haematobium transmission.