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Verfasst von:Yildirim, Timur Mert [VerfasserIn]   i
 Auffarth, Gerd U. [VerfasserIn]   i
 Son, Hyeck Soo [VerfasserIn]   i
 Khoramnia, Ramin [VerfasserIn]   i
 Munro, Donald John [VerfasserIn]   i
 Merz, Patrick [VerfasserIn]   i
Titel:Dispersive viscosurgical devices demonstrate greater efficacy in protecting corneal endothelium in vitro
Verf.angabe:Timur Mert Yildirim, Gerd U. Auffarth, Hyeck-Soo Son, Ramin Khoramnia, Donald John Munro, Patrick R. Merz
E-Jahr:2019
Jahr:February 16, 2019
Umfang:6 S.
Fussnoten:Gesehen am 22.04.2020
Titel Quelle:Enthalten in: BMJ open ophthalmology
Ort Quelle:London : BMJ Publishing Group, 2016
Jahr Quelle:2019
Band/Heft Quelle:4(2019,1) Artikel-Nummer e000227, 6 Seiten
ISSN Quelle:2397-3269
Abstract:Objective During phacoemulsification, the corneal endothelium is protected by an ophthalmic viscosurgical device (OVD). In this in vitro study, we assessed six different OVDs for their effectiveness in protecting the corneal endothelium. - Methods and analysis Phacoemulsification was performed in cadaver eyes of young pigs. Five syringe units of six different OVDs were tested (Healon EndoCoat, Viscoat, Methylvisc, Healon, Healon GV, ProVisc). After surgery, the area of endothelium coated with OVD was determined in relation to the total endothelial surface. Additionally, an endothelial cell count was obtained. As a control, an endothelial cell count was obtained from freshly trephined corneas. Statistical analysis was performed using the Mann-Whitney U test and the Spearman correlation. - Results The least postoperative endothelial coating and cell count were observed in the cohesive OVDs while the dispersive OVDs showed statistically significant higher values. Healon EndoCoat and Viscoat yielded a coating area of 86 (85-92)% and 85 (85-90)%, respectively. Endothelial cell count was highest in the two dispersive groups with 4065 (3928-4088) cells/mm2 (Methylvisc) and 4032 (4015-4115) cells/mm2 (Viscoat). Endothelial coating area and endothelial cell count correlated statistically significantly. - Conclusion Dispersive OVDs from this study showed greater adherence to the endothelial surface than the cohesive ones. Furthermore, postoperative endothelial cell counts of corneas treated with dispersive OVDs were higher than of corneas treated with cohesive OVDs. Our in vitro results suggest that dispersive OVDs protect the corneal endothelium better during phacoemulsification than cohesive OVDs.
DOI:doi:10.1136/bmjophth-2018-000227
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1136/bmjophth-2018-000227
 Volltext: https://bmjophth.bmj.com/content/4/1/e000227
 DOI: https://doi.org/10.1136/bmjophth-2018-000227
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:corneal endothelium protection
 ophthalmic viscosurgical device
 phacoemulsification
K10plus-PPN:1695653157
Verknüpfungen:→ Zeitschrift

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