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Verfasst von:Wesseling, Pieter [VerfasserIn]   i
 Capper, David [VerfasserIn]   i
Titel:WHO 2016 classification of gliomas
Verf.angabe:P. Wesseling, and D. Capper
Jahr:2018
Umfang:12 S.
Teil:volume:44
 year:2018
 number:2
 pages:139-150
 extent:12
Fussnoten:First published: 16 August 2017 ; Gesehen am 23.04.2020
Titel Quelle:Enthalten in: Neuropathology & applied neurobiology
Ort Quelle:Oxford [u.a.] : Wiley-Blackwell, 1975
Jahr Quelle:2018
Band/Heft Quelle:44(2018), 2, Seite 139-150
ISSN Quelle:1365-2990
Abstract:Gliomas are the most frequent intrinsic tumours of the central nervous system and encompass two principle subgroups: diffuse gliomas and gliomas showing a more circumscribed growth pattern (‘nondiffuse gliomas’). In the revised fourth edition of the WHO Classification of CNS tumours published in 2016, classification of especially diffuse gliomas has fundamentally changed: for the first time, a large subset of these tumours is now defined based on presence/absence of IDH mutation and 1p/19q codeletion. Following this approach, the diagnosis of (anaplastic) oligoastrocytoma can be expected to largely disappear. Furthermore, in the WHO 2016 Classification gliomatosis cerebri is not an entity anymore but is now considered as a growth pattern. The most important changes in the very diverse group of ‘nondiffuse’ gliomas and neuronal-glial tumours are the introduction of anaplastic pleomorphic xanthoastrocytoma, of diffuse leptomeningeal glioneuronal tumour and of RELA fusion-positive ependymoma as entities. In the last part of this review, after very briefly touching upon classification of neuronal, choroid plexus and pineal region tumours, some practical implications and challenges associated with the WHO 2016 Classification of gliomas are discussed.
DOI:doi:10.1111/nan.12432
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1111/nan.12432
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/nan.12432
 DOI: https://doi.org/10.1111/nan.12432
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:1p/19q codeletion
 astrocytoma
 classification
 glioblastoma
 glioma
 IDH mutation
 molecular diagnostics
 oligodendroglioma
 World Health Organization
K10plus-PPN:1695803817
Verknüpfungen:→ Zeitschrift

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