Depression and resting state heart rate variability in children and adolescents

• Verfasst von: Koenig, Julian [VerfasserIn]
• Verfasst von: Kemp, Andrew H. [VerfasserIn]
• Verfasst von: Beauchaine, Theodore P. [VerfasserIn]
• Verfasst von: Thayer, Julian F. [VerfasserIn]
• Verfasst von: Kaess, Michael [VerfasserIn]
• Titel: Depression and resting state heart rate variability in children and adolescents
• Titelzusatz: a systematic review and meta-analysis
• Verf.angabe: Julian Koenig, Andrew H. Kemp, Theodore P. Beauchaine, Julian F. Thayer, Michael Kaess
• E-Jahr: 2016
• Jahr: 27 April 2016
• Umfang: 15 S.
• Fussnoten: Gesehen am 29.04.2020
• Titel Quelle: Enthalten in: Clinical psychology review
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1981
• Jahr Quelle: 2016
• Band/Heft Quelle: 46(2016), Seite 136-150
• ISSN Quelle: 1873-7811
• DOI: doi:10.1016/j.cpr.2016.04.013
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Adolescents
• Sach-SW: Children
• Sach-SW: Depression
• Sach-SW: Depressive symptoms
• Sach-SW: Heart rate variability
• Sach-SW: Vagal activity
• K10plus-PPN: 1696845890

Abstract

Among adults, depression is associated with reduced vagal activity, as indexed by high frequency heart rate variability [HF-HRV]), which correlates inversely with depression severity. Available evidence in depressed children and adolescents remains to be reviewed systematically. A search of the literature was performed to identify studies reporting (i) HF-HRV in clinically depressed children/adolescents relative to controls (k=4, n=259) and (ii) the association between HF-HRV and depressive symptoms as measured by standardized psychometric instruments in children and adolescents (k=6, n=2625). Random-effects meta-analysis on group differences revealed significant effects that were associated with a moderate effect size (Hedges' g=−0.59; 95% CI [−1.05; −0.13]), indicating lower resting state HF-HRV among clinically depressed children/adolescents (n=99) compared to healthy controls (n=160), consistent with findings among adults. While no correlation between HF-HRV and depressive symptom severity was observed (r=−.041 [−0.143; 0.062]), these additional correlational findings are limited to non-clinical samples. Findings have important clinical implications including a potentially increased risk for future physical ill health and also the identification of potential new treatment targets in child and adolescent depression.