| |  Online-Ressource |
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| Verfasst von: | Pawlitzki, Marc [VerfasserIn]  |
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| | Campe, Christin [VerfasserIn] |
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| | Rolfes, Leoni [VerfasserIn] |
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| | Heinze, Hans-Jochen [VerfasserIn] |
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| | Leypoldt, Frank [VerfasserIn] |
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| | Wandinger, Klaus-Peter [VerfasserIn] |
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| | Reindl, Markus [VerfasserIn] |
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| | Wildemann, Brigitte [VerfasserIn] |
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| | Jarius, Sven [VerfasserIn] |
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| | Körtvélyessy, Péter [VerfasserIn] |
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| Titel: | Transient MOG antibody seroconversion associated with immunomodulating therapy |
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| Verf.angabe: | Marc Pawlitzki, Christin Campe, Leoni Rolfes, Hans-Jochen Heinze, Frank Leypoldt, Klaus-Peter Wandinger, Markus Reindl, Brigitte Wildemann, Sven Jarius, Peter Körtvelyessy |
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| Jahr: | 2020 |
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| Jahr des Originals: | 2019 |
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| Umfang: | 3 S. |
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| Fussnoten: | Gesehen am 04.05.2020 ; Available online: 28 September 2019 ; Immunoglobulin G (IgG) autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG) have recently been associated with autoimmune CNS demyelination. We present the case of a 35-year-old patient who was seronegative for MOG-IgG (as confirmed by means of three independent immunoassays) during two corticosteroid-responsive attacks of brainstem encephalitis and optic neuritis, respectively, but turned positive for MOG-IgG under treatment with interferon-beta (IFN-beta), which was commenced 6 months after onset of the first attack. MOG-IgG serum levels declined after therapy was switched to glatiramer acetate. The fact that seroconversion was first observed under treatment with IFN-beta is in accordance with previous evidence suggesting a role of IFN-beta in disease exacerbation in antibody-mediated disorders |
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| Titel Quelle: | Enthalten in: Multiple Sclerosis and Related Disorders |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 2012 |
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| Jahr Quelle: | 2020 |
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| Band/Heft Quelle: | 37(2020) Artikel-Nummer 101420, 3 Seiten |
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| ISSN Quelle: | 2211-0356 |
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| DOI: | doi:10.1016/j.msard.2019.101420 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.msard.2019.101420 |
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| | DOI: https://doi.org/10.1016/j.msard.2019.101420 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1694034496 |
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| Verknüpfungen: | → Zeitschrift |
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Transient MOG antibody seroconversion associated with immunomodulating therapy / Pawlitzki, Marc [VerfasserIn]; 2020 (Online-Ressource)
