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Status: Bibliographieeintrag

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Verfasst von:Ali, Sharib [VerfasserIn]   i
 Wörz, Stefan [VerfasserIn]   i
 Amunts, Katrin [VerfasserIn]   i
 Eils, Roland [VerfasserIn]   i
 Axer, Markus [VerfasserIn]   i
 Rohr, Karl [VerfasserIn]   i
Titel:Rigid and non-rigid registration of polarized light imaging data for 3D reconstruction of the temporal lobe of the human brain at micrometer resolution
Verf.angabe:Sharib Ali, Stefan Wörz, Katrin Amunts, Roland Eils, Markus Axer, Karl Rohr
E-Jahr:2018
Jahr:6 July 2018
Umfang:17 S.
Fussnoten:Gesehen am 04.05.2020
Titel Quelle:Enthalten in: NeuroImage
Ort Quelle:Orlando, Fla. : Academic Press, 1992
Jahr Quelle:2018
Band/Heft Quelle:181(2018), Seite 235-251
ISSN Quelle:1095-9572
Abstract:To understand the spatial organization as well as long- and short-range connections of the human brain at microscopic resolution, 3D reconstruction of histological sections is important. We approach this challenge by reconstructing series of unstained histological sections of multi-scale (1.3μm and 64μm) and multi-modal 3D polarized light imaging (3D-PLI) data. Since spatial coherence is lost during the sectioning procedure, image registration is the major step in 3D reconstruction. We propose a non-rigid registration method which comprises of a novel multi-modal similarity metric and an improved regularization scheme to cope with deformations inevitably introduced during the sectioning procedure, as well as a rigid registration approach using a robust similarity metric for improved initial alignment. We also introduce a multi-scale feature-based localization and registration approach for mapping of 1.3μm sections to 64μm sections and a scale-adaptive method that can handle challenging sections with large semi-global deformations due to tissue splits. We have applied our registration method to 126 consecutive sections of the temporal lobe of the human brain with 64μm and 1.3μm resolution. Each step of the registration method was quantitatively evaluated using 10 different sections and manually determined ground truth, and a quantitative comparison with previous methods was performed. Visual assessment of the reconstructed volumes and comparison with reference volumes confirmed the high quality of the registration result.
DOI:doi:10.1016/j.neuroimage.2018.06.084
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.neuroimage.2018.06.084
 Volltext: http://www.sciencedirect.com/science/article/pii/S1053811918305913
 DOI: https://doi.org/10.1016/j.neuroimage.2018.06.084
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:3D reconstruction
 Canonical correlation transform
 Hippocampus
 Human brain
 Image registration
 Polarized light imaging
K10plus-PPN:1697106218
Verknüpfungen:→ Zeitschrift

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