Prevalence of contact allergy to p-phenylenediamine in the European general population

• Verfasst von: Diepgen, Thomas L. [VerfasserIn]
• Verfasst von: Naldi, Luigi [VerfasserIn]
• Verfasst von: Bruze, Magnus [VerfasserIn]
• Verfasst von: Cazzaniga, Simone [VerfasserIn]
• Verfasst von: Schuttelaar, Marie-Louise [VerfasserIn]
• Verfasst von: Elsner, Peter [VerfasserIn]
• Verfasst von: Goncalo, Margarida [VerfasserIn]
• Verfasst von: Ofenloch, Robert [VerfasserIn]
• Verfasst von: Svensson, Åke [VerfasserIn]
• Titel: Prevalence of contact allergy to p-phenylenediamine in the European general population
• Verf.angabe: Thomas L. Diepgen, Luigi Naldi, Magnus Bruze, Simone Cazzaniga, Marie-Louise Schuttelaar, Peter Elsner, Margarida Goncalo, Robert Ofenloch and Åke Svensson
• Jahr: 2016
• Jahr des Originals: 2015
• Umfang: 7 S.
• Fussnoten: Accepted 18 September 2015 ; Gesehen am 08.05.2020
• Titel Quelle: Enthalten in: The journal of investigative dermatology
• Ort Quelle: Amsterdam : Elsevier, 1938
• Jahr Quelle: 2016
• Band/Heft Quelle: 136(2016), 2, Seite 409-415
• ISSN Quelle: 1523-1747
• DOI: doi:10.1016/j.jid.2015.10.064
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1697734871

Abstract

Population-based studies on contact allergy to <i>p</i>-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a random sample (n = 2,739) was patch tested to PPD. Overall, 5,286 individuals (50.9%) reported having used hair colorants at least once in their lifetime (78% female, 20% male), and 35% had used hair colorants during the last 12 months. Hair colorant avoidance because of any skin problem during the lifetime was reported by 6%. Black henna tattoos had been used by 5.5% during their lifetime. The prevalence of PPD contact allergy was 0.8% (95% confidence interval 0.6-1.0%), with no statistically significant association with gender or hair dye use. The prevalence of PPD in black henna tattoo users was 3.2% versus 0.6% in nonusers (<i>P</i> < 0.001). A clinically relevant positive patch test reaction to PPD related to hair coloring products was found in 0.1% (95% confidence interval 0.0-0.2%). A significant association with PPD contact allergy was observed for subjects who had black henna tattoos in their lifetime, with an age- and gender-adjusted odds ratio of 9.33 (95% confidence interval 3.45-25.26, <i>P</i> < 0.001). Black henna tattoos are an important risk factor for PPD contact allergy.