| |  Online-Ressource |
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| Verfasst von: | Scheuring, David [VerfasserIn]  |
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| | Löfke, Christian [VerfasserIn] |
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| | Krüger, Falco [VerfasserIn] |
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| | Kittelmann, Maike [VerfasserIn] |
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| | Eisa, Ahmed [VerfasserIn] |
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| | Hughes, Louise [VerfasserIn] |
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| | Smith, Richard S. [VerfasserIn] |
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| | Hawes, Chris [VerfasserIn] |
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| | Schumacher, Karin [VerfasserIn] |
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| | Kleine-Vehn, Jürgen [VerfasserIn] |
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| Titel: | Actin-dependent vacuolar occupancy of the cell determines auxin-induced growth repression |
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| Verf.angabe: | David Scheuring, Christian Löfke, Falco Krüger, Maike Kittelmann, Ahmed Eisa, Louise Hughes, Richard S. Smith, Chris Hawes, Karin Schumacher, and Jürgen Kleine-Vehn |
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| Jahr: | 2016 |
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| Jahr des Originals: | 2015 |
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| Umfang: | 6 S. |
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| Fussnoten: | First published December 29, 2015 ; Gesehen am 13.05.2020 |
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| Titel Quelle: | Enthalten in: National Academy of Sciences (Washington, DC)Proceedings of the National Academy of Sciences of the United States of America |
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| Ort Quelle: | Washington, DC : National Acad. of Sciences, 1915 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 113(2016), 2, Seite 452-457 |
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| ISSN Quelle: | 1091-6490 |
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| Abstract: | The cytoskeleton is an early attribute of cellular life, and its main components are composed of conserved proteins. The actin cytoskeleton has a direct impact on the control of cell size in animal cells, but its mechanistic contribution to cellular growth in plants remains largely elusive. Here, we reveal a role of actin in regulating cell size in plants. The actin cytoskeleton shows proximity to vacuoles, and the phytohormone auxin not only controls the organization of actin filaments but also impacts vacuolar morphogenesis in an actin-dependent manner. Pharmacological and genetic interference with the actin-myosin system abolishes the effect of auxin on vacuoles and thus disrupts its negative influence on cellular growth. SEM-based 3D nanometer-resolution imaging of the vacuoles revealed that auxin controls the constriction and luminal size of the vacuole. We show that this actin-dependent mechanism controls the relative vacuolar occupancy of the cell, thus suggesting an unanticipated mechanism for cytosol homeostasis during cellular growth. |
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| DOI: | doi:10.1073/pnas.1517445113 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1073/pnas.1517445113 |
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| | Volltext: https://www.pnas.org/content/113/2/452 |
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| | DOI: https://doi.org/10.1073/pnas.1517445113 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | actin cytoskeleton |
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| | auxin |
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| | cell growth |
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| | vacuole |
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| K10plus-PPN: | 1698149085 |
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| Verknüpfungen: | → Zeitschrift |
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Actin-dependent vacuolar occupancy of the cell determines auxin-induced growth repression / Scheuring, David [VerfasserIn]; 2016 (Online-Ressource)
