Status: Bibliographieeintrag
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| Verfasst von: | Migliorini, Elisa [VerfasserIn]  |
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| | Valat, Anne [VerfasserIn] |
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| | Picart, Catherine [VerfasserIn] |
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| | Cavalcanti-Adam, Elisabetta A. [VerfasserIn] |
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| Titel: | Tuning cellular responses to BMP-2 with material surfaces |
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| Verf.angabe: | Elisa Migliorini, Anne Valat, Catherine Picart, Elisabetta Ada Cavalcanti-Adam |
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| Jahr: | 2016 |
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| Jahr des Originals: | 2015 |
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| Umfang: | 10 S. |
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| Fussnoten: | Published online: 3 December 2015 ; Gesehen am 15.05.2020 |
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| Titel Quelle: | Enthalten in: Cytokine & growth factor reviews |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1989 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 27(2016), Seite 43-54 |
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| ISSN Quelle: | 1879-0305 |
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| Abstract: | Bone morphogenetic protein 2 (BMP-2) has been known for decades as a strong osteoinductive factor and for clinical applications is combined solely with collagen as carrier material. The growing concerns regarding side effects and the importance of BMP-2 in several developmental and physiological processes have raised the need to improve the design of materials by controlling BMP-2 presentation. Inspired by the natural cell environment, new material surfaces have been engineered and tailored to provide both physical and chemical cues that regulate BMP-2 activity. Here we describe surfaces designed to present BMP-2 to cells in a spatially and temporally controlled manner. This is achieved by trapping BMP-2 using physicochemical interactions, either covalently grafted or combined with other extracellular matrix components. In the near future, we anticipate that material science and biology will integrate and further develop tools for in vitro studies and potentially bring some of them toward in vivo applications. |
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| DOI: | doi:10.1016/j.cytogfr.2015.11.008 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.cytogfr.2015.11.008 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S1359610115300101 |
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| | DOI: https://doi.org/10.1016/j.cytogfr.2015.11.008 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | BMP receptors |
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| | BMP-2 |
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| | Cell adhesion |
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| | Growth factor immobilization |
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| | Material surface |
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| | Signaling |
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| K10plus-PPN: | 1698320191 |
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| Verknüpfungen: | → Zeitschrift |
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Tuning cellular responses to BMP-2 with material surfaces / Migliorini, Elisa [VerfasserIn]; 2016 (Online-Ressource)
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