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| Verfasst von: | Longuespée, Rémi [VerfasserIn]  |
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| | Casadonte, Rita [VerfasserIn] |
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| | Kriegsmann, Mark [VerfasserIn] |
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| | Pottier, Charles [VerfasserIn] |
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| | Muller, Gaël Picard de [VerfasserIn] |
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| | Delvenne, Philippe [VerfasserIn] |
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| | Kriegsmann, Jörg [VerfasserIn] |
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| | Pauw, Edwin De [VerfasserIn] |
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| Titel: | MALDI mass spectrometry imaging |
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| Titelzusatz: | a cutting-edge tool for fundamental and clinical histopathology |
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| Verf.angabe: | Rémi Longuespée, Rita Casadonte, Mark Kriegsmann, Charles Pottier, Gaël Picard de Muller, Philippe Delvenne, Jörg Kriegsmann and Edwin De Pauw |
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| E-Jahr: | 2016 |
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| Jahr: | 17 May 2016 |
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| Umfang: | 19 S. |
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| Fussnoten: | Gesehen am 18.05.2020 |
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| Titel Quelle: | Enthalten in: Proteomics / Clinical applications |
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| Ort Quelle: | Weinheim : Wiley VCH, 2007 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 10(2016), 7, Seite 701-719 |
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| ISSN Quelle: | 1862-8354 |
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| Abstract: | Histopathological diagnoses have been done in the last century based on hematoxylin and eosin staining. These methods were complemented by histochemistry, electron microscopy, immunohistochemistry (IHC), and molecular techniques. Mass spectrometry (MS) methods allow the thorough examination of various biocompounds in extracts and tissue sections. Today, mass spectrometry imaging (MSI), and especially matrix-assisted laser desorption ionization (MALDI) imaging links classical histology and molecular analyses. Direct mapping is a major advantage of the combination of molecular profiling and imaging. MSI can be considered as a cutting edge approach for molecular detection of proteins, peptides, carbohydrates, lipids, and small molecules in tissues. This review covers the detection of various biomolecules in histopathological sections by MSI. Proteomic methods will be introduced into clinical histopathology within the next few years. |
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| DOI: | doi:10.1002/prca.201500140 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1002/prca.201500140 |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201500140 |
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| | DOI: https://doi.org/10.1002/prca.201500140 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Histology |
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| | Imaging |
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| | MALDI |
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| | Mass spectrometry |
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| | Omics |
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| | Pathology |
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| K10plus-PPN: | 1698452756 |
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| Verknüpfungen: | → Zeitschrift |
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MALDI mass spectrometry imaging / Longuespée, Rémi [VerfasserIn]; 17 May 2016 (Online-Ressource)
