Status: Bibliographieeintrag
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| Verfasst von: | Ferreira, Gustavo Dias [VerfasserIn]  |
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| | Capp, Edison [VerfasserIn] |
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| | Jauckus, Julia [VerfasserIn] |
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| | Strowitzki, Thomas [VerfasserIn] |
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| | Germeyer, Ariane [VerfasserIn] |
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| Titel: | Expression of semaphorin class 3 is higher in the proliferative phase on the human endometrium |
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| Verf.angabe: | Gustavo Dias Ferreira, Edison Capp, Julia Jauckus, Thomas Strowitzki, Ariane Germeyer |
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| E-Jahr: | 2018 |
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| Jahr: | 15 February 2018 |
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| Umfang: | 5 S. |
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| Fussnoten: | Gesehen am 19.05.2020 |
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| Titel Quelle: | Enthalten in: Archives of gynecology and obstetrics |
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| Ort Quelle: | Berlin : Springer, 1870 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 297(2018), 5, Seite 1175-1179 |
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| ISSN Quelle: | 1432-0711 |
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| Abstract: | Purpose: The semaphorins are related to angiogenesis and cell proliferation depending on the tissue. The purpose of this study was to assess gene expression of class 3 semaphorin (SEMA3A-F) and protein expression of semaphorin 3A (SEMA3A) within human endometrium throughout the menstrual cycle. Methods: Gene expression of SEMA3A-F was analyzed by real-time PCR (qRT-PCR) and protein expression of SEMA3A was analyzed by ELISA in endometrial biopsies in the proliferative and secretory phase of the menstrual cycle. Results: Gene expression of SEMA3A, SEMA3C, SEMA3D, and SEMA3E was statistically significant decreased in secretory compared to proliferative phase endometrium (p < 0.05). Accordingly, SEMA3A protein expression in the secretory phase was lower than protein expression in proliferative phase endometrium (p ≤ 0.05). Conclusion: SEMA3A, 3C, 3D, and 3E are possibly related to cell proliferation in the endometrium, being more expressed in the proliferative phase of the cycle. This finding may stimulate studies of class 3 semaphorins as a possible target for treatment of endometrial pathologies. |
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| DOI: | doi:10.1007/s00404-018-4719-3 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s00404-018-4719-3 |
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| | DOI: https://doi.org/10.1007/s00404-018-4719-3 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1698516738 |
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| Verknüpfungen: | → Zeitschrift |
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Expression of semaphorin class 3 is higher in the proliferative phase on the human endometrium / Ferreira, Gustavo Dias [VerfasserIn]; 15 February 2018 (Online-Ressource)
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