| |  Online-Ressource |
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| Verfasst von: | Geier, Johannes [VerfasserIn]  |
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| | Lessmann, Holger [VerfasserIn] |
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| | Hillen, Uwe [VerfasserIn] |
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| | Skudlik, Christoph [VerfasserIn] |
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| | Jappe, Uta [VerfasserIn] |
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| Titel: | Sensitization to reactive diluents and hardeners in epoxy resin systems |
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| Titelzusatz: | IVDK data 2002-2011$dpart II: concomitant reactions |
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| Verf.angabe: | Johannes Geier, Holger Lessmann, Uwe Hillen, Christoph Skudlik and Uta Jappe |
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| Jahr: | 2016 |
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| Jahr des Originals: | 2015 |
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| Umfang: | 8 S. |
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| Fussnoten: | Accepted for publication: 21 September 2015 ; Gesehen am 22.05.2020 |
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| Titel Quelle: | Enthalten in: Contact dermatitis |
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| Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1975 |
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| Jahr Quelle: | 2016 |
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| Band/Heft Quelle: | 74(2016), 2, Seite 94-101 |
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| ISSN Quelle: | 1600-0536 |
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| Abstract: | BACKGROUND: Beside the basic resins, reactive diluents and hardeners are important sensitizers in epoxy resin systems (ERSs). Because of chemical similarities, immunological cross-reactivity may occur. - OBJECTIVES: To analyse concomitant reactivity among reactive diluents and hardeners in the patients concerned, as one integral part of a research project on the sensitizing capacity of ERSs (FP-0324). - METHODS: A retrospective analysis of data from the Information Network of Departments of Dermatology (IVDK), 2002-2011, was performed. - RESULTS: There was close concomitant reactivity to 1,6-hexanediol diglycidyl ether and 1,4-butanediol diglycidyl ether (1,4-BDDGE), and to phenyl glycidyl ether (PGE) and cresyl glycidyl ether (CGE), whereas reactions to p-tert-butylphenyl glycidyl ether occurred more independently from those to PGE and CGE. Concomitant reactions to butyl glycidyl ether and 1,4-BDDGE may point to a common allergenic compound derived from the metabolism of 1,4-BDDGE. Among the structurally more diverse group of hardeners, there was no evidence of immunological cross-reactions. - CONCLUSIONS: More detailed knowledge of cross-reactivity among ERS components facilitates the interpretation of patch test results and will allow safer ERSs to be composed in the future. |
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| DOI: | doi:10.1111/cod.12490 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1111/cod.12490 |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.12490 |
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| | DOI: https://doi.org/10.1111/cod.12490 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Adult |
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| | Austria |
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| | Butylene Glycols |
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| | concomitant reactivity |
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| | cross-reactivity |
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| | Dermatitis, Allergic Contact |
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| | Dermatitis, Occupational |
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| | Epoxy Compounds |
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| | epoxy resin systems |
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| | Epoxy Resins |
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| | Female |
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| | Germany |
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| | Hand Dermatoses |
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| | hardeners |
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| | Humans |
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| | Male |
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| | Middle Aged |
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| | occupational contact allergy |
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| | Patch Tests |
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| | reactive diluents |
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| | Retrospective Studies |
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| | Risk Factors |
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| | Switzerland |
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| | Young Adult |
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| K10plus-PPN: | 1698698941 |
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| Verknüpfungen: | → Zeitschrift |
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Sensitization to reactive diluents and hardeners in epoxy resin systems / Geier, Johannes [VerfasserIn]; 2016 (Online-Ressource)
