Insights into auditory cortex dynamics from non-invasive brain stimulation

• Verfasst von: Andoh, Jamila [VerfasserIn]
• Verfasst von: Matsushita, Reiko [VerfasserIn]
• Verfasst von: Zatorre, Robert J. [VerfasserIn]
• Titel: Insights into auditory cortex dynamics from non-invasive brain stimulation
• Verf.angabe: Jamila Andoh, Reiko Matsushita, and Robert J. Zatorre
• E-Jahr: 2018
• Jahr: 13 July 2018
• Umfang: 11 S.
• Fussnoten: Gesehen am 27.05.2020
• Titel Quelle: Enthalten in: Frontiers in neuroscience
• Ort Quelle: Lausanne : Frontiers Research Foundation, 2007
• Jahr Quelle: 2018
• Band/Heft Quelle: 12(2018) Artikel-Nummer 469, 11 Seiten
• ISSN Quelle: 1662-453X
• DOI: doi:10.3389/fnins.2018.00469
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: asymmetry
• Sach-SW: Auditory Cortex
• Sach-SW: Interhemispheric interactions
• Sach-SW: network dynamics
• Sach-SW: Non-invasive brain stimulation (NIBS)
• K10plus-PPN: 1698895801

Abstract

Non-invasive brain stimulation (NIBS) has been widely used as a research tool to modulate cortical excitability of motor as well as non-motor areas, including auditory or language-related areas. NIBS, especially transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), have also been used in clinical settings, with however variable therapeutic outcome, highlighting the need to better understand the mechanisms underlying NIBS techniques. TMS was initially used to address causality between specific brain areas and related behaviour, such as language production, providing non-invasive alternatives to lesion studies. Recent literature however suggests that the relationship is not as straightforward as originally thought, and that TMS can show both linear and non-linear modulation of brain responses, highlighting complex network dynamics. In particular, in the last decade, NIBS studies have enabled further advances in our understanding of auditory processing and its underlying functional organization. For instance, NIBS studies showed that even when only one auditory cortex is stimulated unilaterally, bilateral modulation may result, highlighting the influence of functional connectivity between auditory cortices. Additional neuromodulation techniques such as transcranial alternating current stimulation or transcranial random noise stimulation have been used to target frequency-specific neural oscillations of the auditory cortex, providing further insight into modulation of auditory functions. All these NIBS techniques offer different perspectives into the function and organization of auditory cortex. However, further research should be carried out to assess the mode of action and long-term effects of NIBS to optimize their use in clinical settings.