| |  Online-Ressource |
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| Verfasst von: | Flechsig, Paul [VerfasserIn]  |
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| | Zechmann, Christian [VerfasserIn] |
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| | Schreiweis, Julian [VerfasserIn] |
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| | Kratochwil, Clemens [VerfasserIn] |
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| | Rath, Daniel [VerfasserIn] |
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| | Schwartz, Lawrence H. [VerfasserIn] |
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| | Schlemmer, Heinz-Peter [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Haberkorn, Uwe [VerfasserIn] |
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| | Giesel, Frederik L. [VerfasserIn] |
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| Titel: | Qualitative and quantitative image analysis of CT and MR imaging in patients with neuroendocrine liver metastases in comparison to 68Ga-DOTATOC PET |
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| Verf.angabe: | Paul Flechsig, Christian M. Zechmann, Julian Schreiweis, Clemens Kratochwil, Daniel Rath, Lawrence H. Schwartz, Heinz-Peter Schlemmer, Hans-Ulrich Kauczor, Uwe Haberkorn, Frederik L. Giesel |
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| E-Jahr: | 2015 |
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| Jahr: | 8 May 2015 |
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| Umfang: | 8 S. |
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| Fussnoten: | Im Titel ist "68" hochgestellt ; Gesehen am 02.06.2020 |
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| Titel Quelle: | Enthalten in: European journal of radiology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1990 |
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| Jahr Quelle: | 2015 |
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| Band/Heft Quelle: | 84(2015), 8, Seite 1593-1600 |
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| ISSN Quelle: | 1872-7727 |
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| Abstract: | Purpose - To compare lesion conspicuity in patients with liver metastases arising from gastroenteropancreatic neuroendocrine tumors (GEP-NETs) using MRI, PET and CT. - Materials and methods - 16 patients with GEP-NETs were evaluated using non-contrast MRI, contrast-enhanced (CE) MRI using Gd-EOB-DTPA and CE-68Ga-DOTATOC PET. Quantitative analyses were performed by two blinded readers using ROI-analyses quantifying contrast ratios (CR) between normal liver-tissue and GEP-NET-metastases. Qualitative analyses were performed evaluating primary visibility and spatial detectability of all lesions. - Results - 103 of the same liver metastases were detected on all modalities. Qualitatively, lesion conspicuity was superior on CE-MRI imaging compared to non-contrast MR-sequences (T2, DWI, fl2D, fl3D), as well as arterial- and portal-venous phase CT. Concerning detectability of lesions, CE-MRI was superior to all other modalities. The quantitative ROI-analysis demonstrated improved CR for DWI compared to all other non-contrast MR-sequences (p<0.001). CE-MRI presented with higher CR-values compared to CE-68Ga-DOTATOC PET/CT (p<0.001). - Conclusions - Anatomic imaging using non contrast MRI with fl2D-and fl3D-sequences in combination with the molecular imaging modality 68Ga-DOTATOC PET is optimal for the assessment of liver lesions in GEP-NET-patients. Even though CE-MRI was superior to non-contrast MRI, non-contrast MRI is sufficient to detect and quantify liver metastases in daily routine, especially in combination with DW-Imaging. |
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| DOI: | doi:10.1016/j.ejrad.2015.04.009 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.ejrad.2015.04.009 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X15001837 |
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| | DOI: https://doi.org/10.1016/j.ejrad.2015.04.009 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Computed tomography |
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| | Gastroenteropancreatic neuroendocrine tumors |
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| | Magnetic resonance imaging |
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| | Metastasis |
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| | Positron emission tomography |
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| K10plus-PPN: | 1699199981 |
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| Verknüpfungen: | → Zeitschrift |
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Qualitative and quantitative image analysis of CT and MR imaging in patients with neuroendocrine liver metastases in comparison to 68Ga-DOTATOC PET / Flechsig, Paul [VerfasserIn]; 8 May 2015 (Online-Ressource)
