Interspike intervals reveal functionally distinct cell populations in the medial entorhinal cortex

• Verfasst von: Latuske, Patrick [VerfasserIn]
• Verfasst von: Toader, Oana-Daniela [VerfasserIn]
• Verfasst von: Allen, Kevin [VerfasserIn]
• Titel: Interspike intervals reveal functionally distinct cell populations in the medial entorhinal cortex
• Verf.angabe: Patrick Latuske, Oana Toader, and Kevin Allen
• E-Jahr: 2015
• Jahr: August 5, 2015
• Umfang: 14 S.
• Fussnoten: Gesehen am 09.06.2020
• Titel Quelle: Enthalten in: The journal of neuroscience
• Ort Quelle: Washington, DC : Soc., 1981
• Jahr Quelle: 2015
• Band/Heft Quelle: 35(2015), 31, Seite 10963-10976
• ISSN Quelle: 1529-2401
• DOI: doi:10.1523/JNEUROSCI.0276-15.2015
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: border cells
• Sach-SW: burst
• Sach-SW: entorhinal cortex
• Sach-SW: grid cells
• Sach-SW: head-direction cells
• K10plus-PPN: 1700250868

Abstract

The superficial layers of the medial entorhinal cortex (MEC) contain spatially selective neurons that are crucial for spatial navigation and memory. These highly specialized neurons include grid cells, border cells, head-direction cells, and irregular spatially selective cells. In addition, MEC neurons display a large variability in their spike patterns at a millisecond time scale. In this study, we analyzed spike trains of neurons in the MEC superficial layers of mice and found that these neurons can be classified into two groups based on their propensity to fire spike doublets at 125-250 Hz.