Status: Bibliographieeintrag
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| Verfasst von: | Redondo Rodríguez, Natalia [VerfasserIn]  |
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| | Madan Renes, Vanesa [VerfasserIn] |
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| | Alvarez, Enrique [VerfasserIn] |
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| | Carrasco, Luis [VerfasserIn] |
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| Titel: | Impact of vesicular stomatitis virus M proteins on different cellular functions |
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| Verf.angabe: | Natalia Redondo, Vanesa Madan, Enrique Alvarez, Luis Carrasco |
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| E-Jahr: | 2015 |
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| Jahr: | June 19, 2015 |
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| Umfang: | 22 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 17.06.2020 |
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| Titel Quelle: | Enthalten in: PLOS ONE |
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| Ort Quelle: | San Francisco, California, US : PLOS, 2006 |
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| Jahr Quelle: | 2015 |
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| Band/Heft Quelle: | 10(2015,6) Artikel-Nummer e0131137, 22 Seiten |
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| ISSN Quelle: | 1932-6203 |
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| Abstract: | Three different matrix (M) proteins termed M1, M2 and M3 have been described in cells infected with vesicular stomatitis virus (VSV). Individual expression of VSV M proteins induces an evident cytopathic effect including cell rounding and detachment, in addition to a partial inhibition of cellular protein synthesis, likely mediated by an indirect mechanism. Analogous to viroporins, M1 promotes the budding of new virus particles; however, this process does not produce an increase in plasma membrane permeability. In contrast to M1, M2 and M3 neither interact with the cellular membrane nor promote the budding of double membrane vesicles at the cell surface. Nonetheless, all three species of M protein interfere with the transport of cellular mRNAs from the nucleus to the cytoplasm and also modulate the redistribution of the splicing factor. The present findings indicate that all three VSV M proteins share some activities that interfere with host cell functions. |
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| DOI: | doi:10.1371/journal.pone.0131137 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1371/journal.pone.0131137 |
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| | Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131137 |
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| | DOI: https://doi.org/10.1371/journal.pone.0131137 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Cell membranes |
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| | Integral membrane proteins |
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| | Membrane proteins |
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| | Messenger RNA |
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| | Protein expression |
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| | Protein translation |
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| | Vesicles |
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| | Vesicular stomatitis virus |
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| K10plus-PPN: | 170073931X |
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| Verknüpfungen: | → Zeitschrift |
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Impact of vesicular stomatitis virus M proteins on different cellular functions / Redondo Rodríguez, Natalia [VerfasserIn]; June 19, 2015 (Online-Ressource)
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