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Verfasst von:Covert, Markus [VerfasserIn]   i
Titel:Fundamentals of Systems Biology
Institutionen:Safari, an O'Reilly Media Company. [MitwirkendeR]   i
Verf.angabe:Covert, Markus
Ausgabe:1st edition
Verlagsort:[Erscheinungsort nicht ermittelbar]
Verlag:CRC Press
Jahr:2015
Umfang:1 online resource (367 pages)
Fussnoten:Online resource; Title from title page (viewed February 4, 2015)
ISBN:978-1-4987-2847-8
 1-4987-2847-2
 1-4200-8411-9
 978-1-4200-8411-5
 978-1-315-22261-5
 1-315-22261-2
 978-1-4200-8410-8
 978-1-4200-8410-8
Abstract:For decades biology has focused on decoding cellular processes one gene at a time, but many of the most pressing biological questions, as well as diseases such as cancer and heart disease, are related to complex systems involving the interaction of hundreds, or even thousands, of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on, carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book's second half, where much more complicated network models are addressed-including transcriptional, signaling, metabolic, and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates, medical students, and biologists new to mathematical modeling) while still having much to offer experienced modelers--whether their interests are microbes, organs, whole organisms, diseases, synthetic biology, or just about any field that investigates living systems.
ComputerInfo:Mode of access: World Wide Web.
URL:Aggregator: https://learning.oreilly.com/library/view/-/9781420084108/?ar
Datenträger:Online-Ressource
Sprache:eng
Bibliogr. Hinweis:Erscheint auch als : Druck-Ausgabe
Sach-SW:Electronic books ; local
 Biologie systémique
 Systèmes biologiques ; Modèles mathématiques
 Biologie moléculaire ; Modèles mathématiques
 Cytologie ; Modèles mathématiques
 Variabilité génétique
 Modèles biologiques
 SCIENCE ; Life Sciences ; Biochemistry
 Human genetics ; Variation
 Biological models
 Molecular biology ; Mathematical models
 Cytology ; Mathematical models
 Biological systems ; Mathematical models
 Systems biology
K10plus-PPN:1702678407
 
 
Lokale URL UB: Zum Volltext
 
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