Small for Size and Flow (SFSF) syndrome

• Verfasst von: Golriz, Mohammad [VerfasserIn]
• Verfasst von: Majlesara, Ali [VerfasserIn]
• Verfasst von: Sakka, Saroa el [VerfasserIn]
• Verfasst von: Ashrafi, Maryam [VerfasserIn]
• Verfasst von: Arwin, Jalal [VerfasserIn]
• Verfasst von: Fard-Rutherford, Nassim [VerfasserIn]
• Verfasst von: Raisi, Hanna [VerfasserIn]
• Verfasst von: Edalatpour, Arman [VerfasserIn]
• Verfasst von: Mehrabi, Arianeb [VerfasserIn]
• Titel: Small for Size and Flow (SFSF) syndrome
• Titelzusatz: an alternative description for posthepatectomy liver failure
• Verf.angabe: Mohammad Golriz, Ali Majlesara, Saroa El Sakka, Maryam Ashrafi, Jalal Arwin, Nassim Fard, Hanna Raisi, Arman Edalatpour, Arianeb Mehrabi
• Jahr: 2016
• Umfang: 9 S.
• Fussnoten: Available online: 26 October 2015 ; Gesehen am 01.07.2020
• Titel Quelle: Enthalten in: Clinics and research in hepatology and gastroenterology
• Ort Quelle: Amsterdam : Elsevier Masson, 2011
• Jahr Quelle: 2016
• Band/Heft Quelle: 40(2016), 3, Seite 267-275
• ISSN Quelle: 2210-741X
• DOI: doi:10.1016/j.clinre.2015.06.024
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1703163192

Abstract

Small for Size Syndrome (SFSS) syndrome is a recognizable clinical syndrome occurring in the presence of a reduced mass of liver, which is insufficient to maintain normal liver function. A definition has yet to be fully clarified, but it is a common clinical syndrome following partial liver transplantation and extended hepatectomy, which is characterized by postoperative liver dysfunction with prolonged cholestasis and coagulopathy, portal hypertension, and ascites. So far, this syndrome has been discussed with focus on the remnant size of the liver after partial liver transplantation or extended hepatectomy. However, the current viewpoints believe that the excessive flow of portal vein for the volume of the liver parenchyma leads to over-pressure, sinusoidal endothelial damages and haemorrhage. The new hypothesis declares that in both extended hepatectomy and partial liver transplantation, progression of Small for Size Syndrome is not determined only by the “size” of the liver graft or remnant, but by the hemodynamic parameters of the hepatic circulation, especially portal vein flow. Therefore, we suggest the term “Small for Size and Flow (SFSF)” for this syndrome. We believe that it is important for liver surgeons to know the pathogenesis and manifestation of this syndrome to react early enough preventing non-reversible tissue damages.