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Status: Bibliographieeintrag

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Verfasst von:Ali-Hassan-Sayegh, Sadegh [VerfasserIn]   i
 Mirhosseini, Seyed Jalil [VerfasserIn]   i
 Tahernejad, Mahbube [VerfasserIn]   i
 Mahdavi, Parisa [VerfasserIn]   i
 Haddad, Fatemeh [VerfasserIn]   i
 Shahidzadeh, Azadeh [VerfasserIn]   i
 Lotfaliani, Mohammad Reza [VerfasserIn]   i
 Sedaghat-Hamedani, Farbod [VerfasserIn]   i
 Kayvanpour, Elham [VerfasserIn]   i
 Weymann, Alexander [VerfasserIn]   i
 Sabashnikov, Anton [VerfasserIn]   i
 Popov, Aron-Frederik [VerfasserIn]   i
Titel:Administration of erythropoietin in patients with myocardial infarction
Titelzusatz:does it make sense? An updated and comprehensive meta-analysis and systematic review
Verf.angabe:Sadegh Ali-Hassan-Sayegh, Seyed Jalil Mirhosseini, Mahbube Tahernejad, Parisa Mahdavi, Fatemeh Haddad, Azadeh Shahidzadeh, Mohammad Reza Lotfaliani, Farbod Sedaghat-Hamedani, Elham Kayvanpour, Alexander Weymann, Anton Sabashnikov, Aron-Frederik Popov
E-Jahr:2015
Jahr:29 January 2015
Umfang:11 S.
Fussnoten:Gesehen am 22.07.2020
Titel Quelle:Enthalten in: Cardiology research and practice
Ort Quelle:New York, NY : Hindawi, 2009
Jahr Quelle:2015
Band/Heft Quelle:16(2015), 3, Seite 179-189
ISSN Quelle:2090-0597
Abstract:This systematic review with meta-analysis sought to determine protective effects of erythropoietin on clinical outcomes following percutaneous coronary intervention (PCI). Medline, Embase, Elsevier and Sciences online database as well as Google scholar literature were used for selecting appropriate studies with randomized controlled design. The effect sizes measured were odds ratio (OR) for categorical variables and weighted mean difference (WMD) with 95% confidence interval for calculating differences between mean values of duration of hospitalization in intervention and control groups. Values of P<0.1 for Q test or I2>50% indicated significant heterogeneity between the studies. The literature searches of all major databases retrieved 973 studies. After screening, a total of 15 trials that reported outcomes were identified. Pooled analysis was performed on left ventricular ejection fraction (WMD of −0.047; 95% CI: −0.912 to 0.819; P=0.9), left ventricular end diastolic volume (WMD of −0.363; 95% CI: −3.902 to 3.175; P=0.8), left ventricular end systolic volume (WMD of 0.346; 95% CI: −2.533 to 3.226; P=0.8), infarct size (WMD of −0.446; 95% CI: −2.352 to −1.460; P=0.6), stroke (OR of 2.1; 95% CI: 0.58 to 7.54; P=0.2), re-myocardial infarction (OR of 1.06; 95% CI: 0.52 to 2.185; P=0.8), heart failure (OR of 0.53; 95% CI: 0.259 to 1.105; P=0.09), mortality (OR of 0.56; 95% CI: 0.27 to 1.19; P=0.13), thrombosis (OR of 0.774; 95% CI: 0.41 to 1.45; P=0.4), major adverse cardiovascular events (OR of 0.926; 95% CI: 0.63 to 1.35; P=0.6). Short-term administration of EPO in patients with myocardial infarction (MI) undergoing PCI does not result in improvement in cardiac function, reduction of infarct size and all-cause mortality. Low dose EPO therapy may not be the choice of treatment for the patients with MI, while higher doses might be more effective.
DOI:doi:10.1016/j.carrev.2015.01.008
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1016/j.carrev.2015.01.008
 Volltext: http://www.sciencedirect.com/science/article/pii/S1553838915000330
 DOI: https://doi.org/10.1016/j.carrev.2015.01.008
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Myocardial infarction
 Clinical outcome
 Erythropoietin
 Percutaneous coronary intervention
K10plus-PPN:1725279088
Verknüpfungen:→ Zeitschrift

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