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Verfasst von:Gompelmann, Daniela [VerfasserIn]   i
 Hofbauer, Tobias [VerfasserIn]   i
 Gerovasili, Vasiliki [VerfasserIn]   i
 Eberhardt, Ralf [VerfasserIn]   i
 Lim, Hyun-ju [VerfasserIn]   i
 Herth, Felix [VerfasserIn]   i
 Heußel, Claus Peter [VerfasserIn]   i
Titel:Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy
Titelzusatz:a retrospective study
Verf.angabe:Daniela Gompelmann, Tobias Hofbauer, Vasiliki Gerovasili, Ralf Eberhardt, Hyun-ju Lim, Felix Herth and Claus-Peter Heussel
E-Jahr:2016
Jahr:24 February 2016
Umfang:7 S.
Teil:volume:21
 year:2016
 number:7
 pages:1255-1261
 extent:7
Fussnoten:Gesehen am 24.07.2020
Titel Quelle:Enthalten in: Respirology
Ort Quelle:Oxford [u.a.] : Wiley-Blackwell, 1996
Jahr Quelle:2016
Band/Heft Quelle:21(2016), 7, Seite 1255-1261
ISSN Quelle:1440-1843
Abstract:Background and objective The aim of endoscopic valve therapy in patients with emphysema is complete lobar atelectasis of the most emphysematous lobe. However, even after the radiological advent of atelectasis, great variability in clinical outcomes can be observed. Methods The baseline clinical measures (vital capacity (VC), forced expiratory flow in 1 s (FEV1), residual volume (RV) and 6-min walk test (6-MWT)) and computed tomography variables (low attenuation volume (LAV) of the target lobe, LAV% of the target and the ipsilateral untreated lobe and LAV of the target lobe to LAV of the target lung and to LAV of the total lung) of 77 patients with complete atelectasis following valve therapy were retrospectively examined to determine their impact on patient´s outcome (changes in VC, FEV1, RV and 6-MWT from baseline to the time of atelectasis). Results Low attenuation volume of the target lobe to LAV of the target lung predicts a significant FEV1 improvement in patients with complete lobar atelectasis following valve therapy. A 10% difference in that computed tomography predictor was associated with a 82-mL improvement in FEV1 (P = 0.006). Lower 6-MWT scores, low VC and high RV at baseline were significantly associated with greater improvement in the respective parameter (all P < 0.001). Conclusion Low attenuation volume of the target lobe to LAV of the target lung and baseline clinical measures seem to significantly predict clinical outcomes in patients with complete lobar atelectasis following valve treatment.
DOI:doi:10.1111/resp.12819
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1111/resp.12819
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.12819
 DOI: https://doi.org/10.1111/resp.12819
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:atelectasis
 computed tomography analysis
 emphysema
 Endoscopic lung volume reduction
 valve therapy
K10plus-PPN:1725499762
Verknüpfungen:→ Zeitschrift

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