Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Rettenmeier, Christoph Alexander [VerfasserIn]  |
| Wadepohl, Hubert [VerfasserIn]  |
| Gade, Lutz H. [VerfasserIn]  |
Titel: | Stereoselective hydrodehalogenation via a radical-based mechanism involving t-shaped chiral nickel(I) pincer complexes |
Verf.angabe: | Christoph Rettenmeier, Hubert Wadepohl, and Lutz H. Gade |
E-Jahr: | 2014 |
Jahr: | 15 July 2014 |
Umfang: | 9 S. |
Fussnoten: | Gesehen am 30.07.2020 |
Titel Quelle: | Enthalten in: Chemistry - a European journal |
Ort Quelle: | Weinheim : Wiley-VCH, 1995 |
Jahr Quelle: | 2014 |
Band/Heft Quelle: | 20(2014), 31, Seite 9657-9665 |
ISSN Quelle: | 1521-3765 |
Abstract: | Abstract We herein report the catalytic enantioselective hydrodehalogenation based on the interplay of a chiral molecular nickel(I)/nickel(II)hydride system. Prochiral geminal dihalogenides are dehalogenated via a secondary configurationally unstable, potentially metal-stabilized radical intermediate. In a subsequent step, the liberated radical is then trapped by the nickel(II) hydrido complex, present in a large excess under the catalytic conditions, which in turn induces the enantioselectivity during the hydrogen atom transfer onto the radical intermediate. These new chiral nickel(I) complexes were found to catalyze the asymmetric hydrodehalogenation of geminal dihalogenides with moderate to good enantiomeric excess values using LiEt3BH as reductant. The main side product generally observed is the dehalogenated alkene, whereas the hydrodehalogenation of the chiral monohalogen compound occurred much more slowly despite the large excess of reductant. |
DOI: | doi:10.1002/chem.201403243 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1002/chem.201403243 |
| Volltext: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.201403243 |
| DOI: https://doi.org/10.1002/chem.201403243 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | asymmetric catalysis |
| dehalogenation |
| enantioselectivity |
| nickel |
| radicals |
K10plus-PPN: | 1725916150 |
Verknüpfungen: | → Zeitschrift |
Stereoselective hydrodehalogenation via a radical-based mechanism involving t-shaped chiral nickel(I) pincer complexes / Rettenmeier, Christoph Alexander [VerfasserIn]; 15 July 2014 (Online-Ressource)
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