| |  Online-Ressource |
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| Verfasst von: | Feng, Wenqian [VerfasserIn]  |
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| | Li, Linxian [VerfasserIn] |
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| | Yang, Chengwu [VerfasserIn] |
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| | Welle, Alexander [VerfasserIn] |
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| | Trapp, Oliver [VerfasserIn] |
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| | Levkin, Pavel A. [VerfasserIn] |
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| Titel: | UV-induced tetrazole-thiol reaction for polymer conjugation and surface functionalization |
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| Verf.angabe: | Wenqian Feng, Linxian Li, Chengwu Yang, Alexander Welle, Oliver Trapp, and Pavel A. Levkin |
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| E-Jahr: | 2015 |
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| Jahr: | June 8, 2015 |
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| Umfang: | 4 S. |
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| Fussnoten: | Gesehen am 03.08.2020 |
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| Titel Quelle: | Enthalten in: Angewandte Chemie / International edition |
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| Ort Quelle: | Weinheim : Wiley-VCH, 1962 |
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| Jahr Quelle: | 2015 |
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| Band/Heft Quelle: | 54(2015), 30, Seite 8732-8735 |
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| ISSN Quelle: | 1521-3773 |
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| Abstract: | A UV-induced 1,3-dipolar nucleophilic addition of tetrazoles to thiols is described. Under UV irradiation the reaction proceeds rapidly at room temperature, with high yields, without a catalyst, and in both polar protic and aprotic solvents, including water. This UV-induced tetrazole-thiol reaction was successfully applied for the synthesis of small molecules, protein modification, and rapid and facile polymer-polymer conjugation. The reaction has also been demonstrated for the formation of micropatterns by site-selective surface functionalization. Superhydrophobic-hydrophilic micropatterns were successfully created by sequential modifications of a tetrazole-modified porous polymer surface with hydrophobic and hydrophilic thiols. A biotin-functionalized surface could be fabricated in aqueous solutions under long-wavelength UV irradiation. |
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| DOI: | doi:10.1002/anie.201502954 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1002/anie.201502954 |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201502954 |
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| | DOI: https://doi.org/10.1002/anie.201502954 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | nucleophilic addition |
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| | photochemistry |
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| | polymer conjugation |
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| | surface modification |
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| | tetrazole-thiol reaction |
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| K10plus-PPN: | 1726061051 |
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| Verknüpfungen: | → Zeitschrift |
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UV-induced tetrazole-thiol reaction for polymer conjugation and surface functionalization / Feng, Wenqian [VerfasserIn]; June 8, 2015 (Online-Ressource)
