Vitamin D and female fertility

• Verfasst von: Lerchbaum, Elisabeth [VerfasserIn]
• Verfasst von: Rabe, Thomas [VerfasserIn]
• Titel: Vitamin D and female fertility
• Verf.angabe: Elisabeth Lerchbaum and Thomas Rabe
• E-Jahr: 2014
• Jahr: June 2014
• Umfang: 6 S.
• Fussnoten: Gesehen am 20.08.2020
• Titel Quelle: Enthalten in: Current opinion in obstetrics and gynecology
• Ort Quelle: London : Lippincott Williams & Wilkins, 1989
• Jahr Quelle: 2014
• Band/Heft Quelle: 26(2014), 3, Seite 145-150
• ISSN Quelle: 1473-656X
• DOI: doi:10.1097/GCO.0000000000000065
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1727531736

Abstract

Purpose of review - Apart from the well known effects of vitamin D on maintaining calcium homeostasis and promoting bone mineralization, there is some evidence suggesting that vitamin D also modulates human reproductive processes. We will review the most interesting and relevant studies on vitamin D and female fertility published over the past year. - Recent findings - In the past year, several observational studies reported a better in-vitro fertilization outcome in women with sufficient vitamin D levels (≥30 ng/ml), which was mainly attributed to vitamin D effects on the endometrium. One randomized controlled trial found an increased endometrial thickness in women with polycystic ovary syndrome (PCOS) receiving vitamin D during intrauterine insemination cycles. Further, vitamin D supplementation had a beneficial effect on serum lipids in PCOS women. Vitamin D treatment improved endometriosis in a rat model and increased vitamin D intake was related to a decreased risk of incident endometriosis. Vitamin D was also favorably associated with primary dysmenorrhea, uterine leiomyoma, and ovarian reserve in late reproductive aged women. - Summary - In women undergoing in-vitro fertilization, a sufficient vitamin D level (≥30 ng/ml) should be obtained. Vitamin D supplementation might improve metabolic parameters in women with PCOS. A high vitamin D intake might be protective against endometriosis.