Status: Bibliographieeintrag
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| Verfasst von: | Frank, Lukas [VerfasserIn]  |
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| | Rippe, Karsten [VerfasserIn] |
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| Titel: | Repetitive RNAs as regulators of chromatin-associated subcompartment formation by phase separation |
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| Verf.angabe: | Lukas Frank and Karsten Rippe |
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| E-Jahr: | 2020 |
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| Jahr: | 19 April 2020 |
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| Umfang: | 17 S. |
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| Fussnoten: | Gesehen am 27.08.2020 |
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| Titel Quelle: | Enthalten in: Journal of molecular biology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1959 |
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| Jahr Quelle: | 2020 |
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| Band/Heft Quelle: | 432(2020), 15, Seite 4270-4286 |
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| ISSN Quelle: | 1089-8638 |
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| Abstract: | Repetitive RNA (repRNA) sequences emerge as important regulators of the dynamic organization of genomic loci into membrane-less subcompartments with distinct nuclear functions. These domains include sites of active transcription like the nucleolus as well as (peri)centromeric and telomeric satellite repeats. Recent studies point to an important role of repRNAs in complex with proteins to promote a phase separation-driven formation of chromatin domains. We review how key features of the phase separation process can be revealed by different experimental approaches and discuss the associated structure-function relationships for chromatin subcompartments that involve repRNA. |
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| DOI: | doi:10.1016/j.jmb.2020.04.015 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.jmb.2020.04.015 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0022283620303028 |
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| | DOI: https://doi.org/10.1016/j.jmb.2020.04.015 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | genome organization |
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| | intrinsically disordered protein region |
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| | liquid-liquid phase separation |
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| | nuclear architecture |
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| | RNA repeats |
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| K10plus-PPN: | 1727889991 |
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| Verknüpfungen: | → Zeitschrift |
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Repetitive RNAs as regulators of chromatin-associated subcompartment formation by phase separation / Frank, Lukas [VerfasserIn]; 19 April 2020 (Online-Ressource)
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