The assessment of Background Parenchymal Enhancement (BPE) in a high-risk population

• Verfasst von: You, Chao [VerfasserIn]
• Verfasst von: Krammer, Julia [VerfasserIn]
• Verfasst von: Schönberg, Stefan [VerfasserIn]
• Verfasst von: Kaiser, Clemens G. [VerfasserIn]
• Titel: The assessment of Background Parenchymal Enhancement (BPE) in a high-risk population
• Titelzusatz: what causes BPE?
• Verf.angabe: Chao You, Anna K. Kaiser, Pascal Baltzer, Julia Krammer, Yajia Gu, Weijun Peng, Stefan O. Schönberg and Clemens G. Kaiser
• E-Jahr: 2018
• Jahr: April 2018
• Umfang: 7 S.
• Fussnoten: Gesehen am 02.09.2020
• Titel Quelle: Enthalten in: Translational oncology
• Ort Quelle: Ann Arbor, Mich. : [Verlag nicht ermittelbar], 2008
• Jahr Quelle: 2018
• Band/Heft Quelle: 11(2018), 2, Seite 243-249
• ISSN Quelle: 1936-5233
• DOI: doi:10.1016/j.tranon.2017.12.006
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1728609755

Abstract

OBJECTIVE: To investigate promoting factors for background parenchymal enhancement (BPE) in MR mammography (MRM). METHODS: 146 patients were retrospectively evaluated, including 91 high-risk patients (50 BRCA patients, 41 patients with elevated lifetime risk). 56 screening patients were matched to the high-risk cases on the basis of age. The correlation of BPE with factors such as fibroglandular tissue (FGT), age, menopausal status, breast cancer, high-risk precondition as well as motion were investigated using linear regression. RESULTS: BPE positively correlated with FGT (P<.001) and negatively correlated with menopausal status (P<.001). Cancer did not show an effect on BPE (P>.05). A high-risk precondition showed a significant impact on the formation of BPE (P<.05). However, when corrected for motion, the correlation between BPE and a high-risk precondition became weak and insignificant, and a highly significant association between BPE and motion was revealed (P<.01). CONCLUSION: BPE positively correlated with FGT and negatively correlated with age. Cancer did not have an effect on BPE. A high-risk precondition appears to have a negative effect on BPE. However, when corrected for motion, high-risk preconditions became insignificant. Technical as well as physiological influences seem to play an important role in the formation of BPE.