| Online-Ressource |
Verfasst von: | Ghamarnejad, Omid [VerfasserIn]  |
| Khajeh, Elias [VerfasserIn]  |
| Rezaei, Nahid [VerfasserIn]  |
| Afshari, Khashayar [VerfasserIn]  |
| Adelian, Ali [VerfasserIn]  |
| Nikdad, Mohammadsadegh [VerfasserIn]  |
| Hoffmann, Katrin [VerfasserIn]  |
| Mehrabi, Arianeb [VerfasserIn]  |
Titel: | Comparative analysis of the discriminatory performance of different well-known risk assessment scores for extended hepatectomy |
Verf.angabe: | Omid Ghamarnejad, Elias Khajeh, Nahid Rezaei, Khashayar Afshari, Ali Adelian, Mohammadsadegh Nikdad, Katrin Hoffmann & Arianeb Mehrabi |
E-Jahr: | 2020 |
Jahr: | 22 January 2020 |
Umfang: | 9 S. |
Fussnoten: | Gesehen am 15.09.2020 |
Titel Quelle: | Enthalten in: Scientific reports |
Ort Quelle: | [London] : Macmillan Publishers Limited, part of Springer Nature, 2011 |
Jahr Quelle: | 2020 |
Band/Heft Quelle: | 10(2020) Artikel-Nummer 930, 9 Seiten |
ISSN Quelle: | 2045-2322 |
Abstract: | The aim of this study was to assess and compare the discriminatory performance of well-known risk assessment scores in predicting mortality risk after extended hepatectomy (EH). A series of 250 patients who underwent EH (≥5 segments resection) were evaluated. Aspartate aminotransferase-to-platelet ratio index (APRI), albumin to bilirubin (ALBI) grade, predictive score developed by Breitenstein et al., liver fibrosis (FIB-4) index, and Heidelberg reference lines charting were used to compute cut-off values, and the sensitivity and specificity of each risk assessment score for predicting mortality were also calculated. Major morbidity and 90-day mortality after EH increased with increasing risk scores. APRI (86%), ALBI (86%), Heidelberg score (81%), and FIB-4 index (79%) had the highest sensitivity for 90-day mortality. However, only the FIB-4 index and Heidelberg score had an acceptable specificity (70% and 65%, respectively). A two-stage risk assessment strategy (Heidelberg-FIB-4 model) with a sensitivity of 70% and a specificity 86% for 90-day mortality was proposed. There is no single specific risk assessment score for patients who undergo EH. A two-stage screening strategy using Heidelberg score and FIB-4 index was proposed to predict mortality after major liver resection. |
DOI: | doi:10.1038/s41598-020-57748-7 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1038/s41598-020-57748-7 |
| Volltext: https://www.nature.com/articles/s41598-020-57748-7 |
| DOI: https://doi.org/10.1038/s41598-020-57748-7 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1732488495 |
Verknüpfungen: | → Zeitschrift |
Comparative analysis of the discriminatory performance of different well-known risk assessment scores for extended hepatectomy / Ghamarnejad, Omid [VerfasserIn]; 22 January 2020 (Online-Ressource)