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Verfasst von:Ghamarnejad, Omid [VerfasserIn]   i
 Khajeh, Elias [VerfasserIn]   i
 Rezaei, Nahid [VerfasserIn]   i
 Afshari, Khashayar [VerfasserIn]   i
 Adelian, Ali [VerfasserIn]   i
 Nikdad, Mohammadsadegh [VerfasserIn]   i
 Hoffmann, Katrin [VerfasserIn]   i
 Mehrabi, Arianeb [VerfasserIn]   i
Titel:Comparative analysis of the discriminatory performance of different well-known risk assessment scores for extended hepatectomy
Verf.angabe:Omid Ghamarnejad, Elias Khajeh, Nahid Rezaei, Khashayar Afshari, Ali Adelian, Mohammadsadegh Nikdad, Katrin Hoffmann & Arianeb Mehrabi
E-Jahr:2020
Jahr:22 January 2020
Umfang:9 S.
Fussnoten:Gesehen am 15.09.2020
Titel Quelle:Enthalten in: Scientific reports
Ort Quelle:[London] : Macmillan Publishers Limited, part of Springer Nature, 2011
Jahr Quelle:2020
Band/Heft Quelle:10(2020) Artikel-Nummer 930, 9 Seiten
ISSN Quelle:2045-2322
Abstract:The aim of this study was to assess and compare the discriminatory performance of well-known risk assessment scores in predicting mortality risk after extended hepatectomy (EH). A series of 250 patients who underwent EH (≥5 segments resection) were evaluated. Aspartate aminotransferase-to-platelet ratio index (APRI), albumin to bilirubin (ALBI) grade, predictive score developed by Breitenstein et al., liver fibrosis (FIB-4) index, and Heidelberg reference lines charting were used to compute cut-off values, and the sensitivity and specificity of each risk assessment score for predicting mortality were also calculated. Major morbidity and 90-day mortality after EH increased with increasing risk scores. APRI (86%), ALBI (86%), Heidelberg score (81%), and FIB-4 index (79%) had the highest sensitivity for 90-day mortality. However, only the FIB-4 index and Heidelberg score had an acceptable specificity (70% and 65%, respectively). A two-stage risk assessment strategy (Heidelberg-FIB-4 model) with a sensitivity of 70% and a specificity 86% for 90-day mortality was proposed. There is no single specific risk assessment score for patients who undergo EH. A two-stage screening strategy using Heidelberg score and FIB-4 index was proposed to predict mortality after major liver resection.
DOI:doi:10.1038/s41598-020-57748-7
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1038/s41598-020-57748-7
 Volltext: https://www.nature.com/articles/s41598-020-57748-7
 DOI: https://doi.org/10.1038/s41598-020-57748-7
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1732488495
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