Advanced diffusion-weighted abdominal imaging

• Verfasst von: Dreher, Constantin [VerfasserIn]
• Verfasst von: Kuder, Tristan Anselm [VerfasserIn]
• Verfasst von: König, Franziska [VerfasserIn]
• Verfasst von: Paech, Daniel [VerfasserIn]
• Verfasst von: Tavakoli, Andrej [VerfasserIn]
• Verfasst von: Laun, Frederik B. [VerfasserIn]
• Verfasst von: Flothow, Florian [VerfasserIn]
• Verfasst von: Gnirs, Regula [VerfasserIn]
• Verfasst von: Benkert, Thomas [VerfasserIn]
• Verfasst von: Strecker, Ralph [VerfasserIn]
• Verfasst von: Schlemmer, Heinz-Peter [VerfasserIn]
• Verfasst von: Bickelhaupt, Sebastian [VerfasserIn]
• Titel: Advanced diffusion-weighted abdominal imaging
• Titelzusatz: qualitative and quantitative comparison of high and ultra-high b-values for lesion detection and image quality
• Verf.angabe: Constantin Dreher, Tristan Anselm Kuder, Franziska König, Daniel Paech, Andrej Tavakoli, Frederik Bernd Laun, Florian Flothow, Regula Gnirs, Thomas Benkert, Ralph Strecker, Heinz-Peter Schlemmer, Sebastian Bickelhaupt
• Jahr: 2020
• Umfang: 8 S.
• Fussnoten: Gesehen am 16.09.2020
• Titel Quelle: Enthalten in: Investigative radiology
• Ort Quelle: Philadelphia, Pa. : Lippincott Williams & Wilkins, 1966
• Jahr Quelle: 2020
• Band/Heft Quelle: 55(2020), 5, Seite 285-292
• ISSN Quelle: 1536-0210
• DOI: doi:10.1097/RLI.0000000000000639
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1733145427

Abstract

Introduction: Magnetic resonance imaging (MRI) of the abdomen increasingly incorporates diffusion-weighted imaging (DWI) sequences. Whereas DWI can substantially aid in detecting and characterizing suspicious findings, it remains unclear to what extent the use of ultra-high b-value DWI might further be of aid for the radiologist especially when using DWI sequences with advanced processing. The target of this study was therefore to compare high and ultra-high b-value DWI in abdominal MRI examinations. Methods: This institutional review board-approved, prospective study included abdominal MRI examinations of 70 oncologic patients (mean age, 58 years; range, 21-90 years) examined with a clinical 1.5 T MRI scanner (MAGNETOM Aera, Siemens Healthcare, Erlangen, Germany) with an advanced echo planar DWI sequence (b = 0, 50, 900, and 1500 s/mm2) after ex vivo phantom and in vivo volunteer investigations. High b900 and ultra-high b1500 DWIs were compared by a qualitative reading for image quality and lesion conspicuity using a 5-point Likert scale with 2 radiologists as readers. The ratios of apparent signal intensities of suspicious lesions/normal tissue of the same organ (LNTRs) were calculated. Appropriate methods were used for statistical analysis, including Wilcoxon signed-rank test and κ statistic for interreader agreement analysis (P < 0.05/0.0125/0.005 after Bonferroni correction). Results: Image quality was significantly increased with b900 as compared with b1500 DWI (P < 0.001) despite using an advanced DWI sequence. A total of 153 suspicious lesions were analyzed. Overall reader confidence for characterization/detection of malignant lesions and, correspondingly, the LNTR (mean, 2.7 ± 1.8 vs 2.4 ± 1.6) were significantly higher with b900 than with b1500 DWI (P < 0.001 and P < 0.001). The increased confidence of lesion recognition and LNTR in the b900 DWI remained significant qualitatively in lymphatic and hepatic lesions and quantitatively in lymphatic, pulmonal, and osseous lesions. Conclusions: Using high b-value DWI (900 s/mm2) provided an improved image quality and also lesion conspicuity as compared with ultra-high b-value DWI (1500 s/mm2) in oncologic abdominal examinations despite using advanced processing. Consequently, the value for additional ultra-high b-value DWI in oncologic examinations should be critically evaluated in future studies.