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Status: Bibliographieeintrag

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Titel:Repositioning of the global epicentre of non-optimal cholesterol
Mitwirkende:Taddei, Cristina [VerfasserIn]   i
 Brenner, Hermann [VerfasserIn]   i
 Saum, Kai-Uwe [VerfasserIn]   i
 Schöttker, Ben [VerfasserIn]   i
 Jonas, Jost B. [VerfasserIn]   i
 Panda-Jonas, Songhomitra [VerfasserIn]   i
 Ahrens, Wolfgang   i
Körperschaft:NCD Risk Factor Collaboration [VerfasserIn]   i
Verf.angabe:NCD Risk Factor Collaboration (NCD-RisC): Cristina Taddei, Hermann Brenner, Jost B. Jonas, Songhomitra Panda-Jonas, Kai-Uwe Saum, Ben Schöttker [und 880 weitere]
E-Jahr:2020
Jahr:3 June 2020
Umfang:24$p73-77
Illustrationen:Diagramme, Karten
Fussnoten:Gesehen am 29.09.2020
Titel Quelle:Enthalten in: Nature
Ort Quelle:London [u.a.] : Nature Publ. Group, 1869
Jahr Quelle:2020
Band/Heft Quelle:582(2020,7810), Seite 73-77, 18 ungezählte Seiten
ISSN Quelle:1476-4687
Abstract:High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.
DOI:doi:10.1038/s41586-020-2338-1
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1038/s41586-020-2338-1
 DOI: https://doi.org/10.1038/s41586-020-2338-1
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:20-year trends
 atherosclerosis society
 blood-pressure
 cardiovascular risk-factors
 density-lipoprotein cholesterol
 heart-disease
 lipids
 medication use
 population
 serum-cholesterol
K10plus-PPN:173395872X
Verknüpfungen:→ Zeitung

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