A systematic review of global alpha-tocopherol status as assessed by nutritional intake levels and blood serum concentrations

• Verfasst von: Péter, Szabolcs [VerfasserIn]
• Verfasst von: Friedel, Angelika [VerfasserIn]
• Verfasst von: Roos, Franz F. [VerfasserIn]
• Verfasst von: Wyss, Adrian [VerfasserIn]
• Verfasst von: Eggersdorfer, Manfred [VerfasserIn]
• Verfasst von: Hoffmann, Kristina [VerfasserIn]
• Verfasst von: Weber, Peter [VerfasserIn]
• Titel: A systematic review of global alpha-tocopherol status as assessed by nutritional intake levels and blood serum concentrations
• Verf.angabe: Szabolcs Péter, Angelika Friedel, Franz F. Roos, Adrian Wyss, Manfred Eggersdorfer, Kristina Hoffmann, and Peter Weber
• E-Jahr: 2016
• Jahr: Juni 14, 2016
• Umfang: 21 S.
• Fussnoten: Gesehen am 07.10.2020
• Titel Quelle: Enthalten in: International journal for vitamin and nutrition research
• Ort Quelle: Singapore : IMR Press, 1999
• Jahr Quelle: 2015
• Band/Heft Quelle: 85(2015), 5-6, Seite 261-281
• ISSN Quelle: 1664-2821
• DOI: doi:10.1024/0300-9831/a000281
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1734978554

Abstract

The purpose of this study is to systematically review the published literature reporting vitamin E intake levels and serum concentrations in order to obtain a global overview of α-tocopherol status. Articles published between 2000 and 2012 were considered; 176 articles referring to 132 single studies were included. Applying an RDA (recommended daily allowance) of 15 mg/day and EAR (estimated average requirement) of 12 mg/day to all populations with a minimum age of 14 years, 82 and 61 % of mean and median data points were below the RDA and the EAR, respectively. Regarding serum concentrations, globally 13 % of the included data points were below the functional deficiency threshold concentration of 12 μmol/L, mostly for newborns and children. Several prospective observational studies suggest that a serum α-tocopherol concentration of ≥30 μmol/L has beneficial effects on human health. Of the reported study populations and subpopulations, only 21 % reached this threshold globally. This systematic review suggests that the α-tocopherol status is inadequate in a substantial part of the studied populations.