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Verfasst von:Dreher, Constantin [VerfasserIn]   i
 Kuder, Tristan Anselm [VerfasserIn]   i
 König, Franziska [VerfasserIn]   i
 Młynarska-Bujny, Anna [VerfasserIn]   i
 Tenconi, Chiara [VerfasserIn]   i
 Paech, Daniel [VerfasserIn]   i
 Schlemmer, Heinz-Peter [VerfasserIn]   i
 Ladd, Mark E. [VerfasserIn]   i
 Bickelhaupt, Sebastian [VerfasserIn]   i
Titel:Radiomics in diffusion data
Titelzusatz:a test-retest, inter- and intra-reader DWI phantom study
Verf.angabe:C. Dreher, T.A. Kuder, F. König, A. Mlynarska-Bujny, C. Tenconi, D. Paech, H.-P. Schlemmer, M.E. Ladd, S. Bickelhaupt
E-Jahr:2020
Jahr:25 July 2020
Umfang:10 S.
Fussnoten:Gesehen am 15.10.2020
Titel Quelle:Enthalten in: Clinical radiology
Ort Quelle:Amsterdam : Elsevier Science, 1960
Jahr Quelle:2020
Band/Heft Quelle:75(2020), 10, Seite 798.e13-798.e22
ISSN Quelle:1365-229X
Abstract:AIM - The aim of this study was to evaluate the robustness of radiomics features of a MRI (magnetic resonance imaging) phantom in quantitative diffusion-weighted imaging (DWI) and depending on the image resolution. - MATERIALS AND METHODS - Scanning of an in-house developed DWI phantom was performed at a 1.5 T MRI scanner (Magnetom AERA, Siemens, Erlangen, Germany) using an echo planar imaging (EPI) DWI sequence (b=0,500,1,000 s/mm2) with low (3×3 mm2) and high (2×2 mm2) image resolutions. Scans were repeated after phantom repositioning to evaluate retest reliability. Radiomics features were extracted after semi-automatic segmentation and standardised pre-processing. Intra-/interobserver reproducibility and test-retest robustness were assessed using intraclass correlation coefficients (ICC). Differences were tested with non-parametric Wilcoxon's signed-rank and Friedman's test (p < 0.05) with Dunn's post-hoc analysis. - RESULTS - Test-retest ICC was overall high with >0.90 for 39/46 radiomics features in all sequences/resolutions. Decreased test-retest ICCs were pronounced for conventional Min-value (overall ICC=0.817), and grey-level zone length matrix (GLZLM) features Short-Zone Emphasis (SZE) and Short-Zone Low Grey-level Emphasis (SZLGE) (for both overall ICC=0.927). Test-retest reproducibility was significantly different between b=500, 1,000 and apparent diffusion coefficient (ADC) (mean 0.975±0.050, 0.974±0.051 and 0.966±0.063), which remained significant after post-hoc analysis between b=1,000 and ADC (p = 0.022). ICCs were not significantly different between resolutions of 2×2 and 3×3 mm2 regarding b=500 (mean: 0.977±0.052 and 0.974±0.049, p = 0.612), b=1,000 (mean: 0.973±0.059 and 0.974±0.054, p = 0.516), and ADC (mean: 0.972±0.049 and 0.955±0.101, p = 0.851). Inter- and intra-observer reliability was consistently high for all sequences (overall mean 0.992±0.021 and 0.990±0.028). - CONCLUSION - Under ex-vivo conditions, DWI provided robust radiomics features with those from ADC being slightly less robust than from raw DWI (b=500, 1,000 s/mm2). No significant difference was detected for different resolutions. Although, ex-vivo reliability of DWI radiomics features was high, no implications can be made regarding in-vivo analyses.
DOI:doi:10.1016/j.crad.2020.06.024
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.crad.2020.06.024
 Volltext: http://www.sciencedirect.com/science/article/pii/S0009926020302579
 DOI: https://doi.org/10.1016/j.crad.2020.06.024
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1735649058
Verknüpfungen:→ Zeitschrift

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