| |  Online-Ressource |
|---|
| Verfasst von: | Oweira, Hani [VerfasserIn]  |
|---|
| | Lahdou, Imad [VerfasserIn] |
|---|
| | Daniel, Volker [VerfasserIn] |
|---|
| | Opelz, Gerhard [VerfasserIn] |
|---|
| | Schmidt, Jan [VerfasserIn] |
|---|
| | Zidan, Ahmed [VerfasserIn] |
|---|
| | Mehrabi, Arianeb [VerfasserIn] |
|---|
| | Sadeghi, Mahmoud [VerfasserIn] |
|---|
| Titel: | Early post-operative acute phase response in patients with early graft dysfunction is predictive of 6-month and 12-month mortality in liver transplant recipients |
|---|
| Verf.angabe: | Hani Oweira, Imad Lahdou, Volker Daniel, Gerhard Opelz, Jan Schmidt, Ahmed Zidan, Arianeb Mehrabi, Mahmoud Sadeghi |
|---|
| E-Jahr: | 2016 |
|---|
| Jahr: | 27 July 2016 |
|---|
| Umfang: | 9 S. |
|---|
| Fussnoten: | Gesehen am 16.10.2020 |
|---|
| Titel Quelle: | Enthalten in: Human immunology |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1980 |
|---|
| Jahr Quelle: | 2016 |
|---|
| Band/Heft Quelle: | 77(2016), 10, Seite 952-960 |
|---|
| ISSN Quelle: | 1879-1166 |
|---|
| Abstract: | Early allograft dysfunction (EAD) after liver transplantation is mostly a reversible event caused by factors related to ischemia/reperfusion (I/R) injury. EAD represents a hepatic injury associated with pre- and early post-transplant inflammatory cytokine responses. Aim of the present study was to evaluate the prognostic and diagnostic value of CRP in liver transplant recipients with EAD. - Materials and methods - Forty-seven patients with EAD were compared with 115 non-EAD patients. Pre- and post-transplant parameters were analyzed. EAD was defined based on postoperative liver function tests such as INR, bilirubin and liver enzymes. Statistical analysis was performed using SPSS version 18.0. - Results - Pre-transplant liver enzyme were not significantly different in the two groups. At day 3, 5 and 10 post-transplant CRP was significantly higher in patients with EAD than in non-EAD patients (p⩽0.001 for all investigations) and remained consistently high in patients with EAD and low in non-EAD patients. EAD patients with high CRP at post-transplant days 3 and 5 showed lower survival at 6-month and 12-month post-transplant than patients with low CRP. - Conclusion - Our results indicate a prognostic and diagnostic value of CRP in patients with early graft dysfunction and predict 6-month and 12-month mortality in liver transplant recipients. |
|---|
| DOI: | doi:10.1016/j.humimm.2016.07.234 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.humimm.2016.07.234 |
|---|
| | Volltext: http://www.sciencedirect.com/science/article/pii/S0198885916303883 |
|---|
| | DOI: https://doi.org/10.1016/j.humimm.2016.07.234 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | CRP |
|---|
| | Early graft dysfunction |
|---|
| | Inflammatory responses |
|---|
| | Transplantation |
|---|
| K10plus-PPN: | 173573926X |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Early post-operative acute phase response in patients with early graft dysfunction is predictive of 6-month and 12-month mortality in liver transplant recipients / Oweira, Hani [VerfasserIn]; 27 July 2016 (Online-Ressource)
