Ultrafast time-resolved spectroscopy of diarylethene-based photoswitchable deoxyuridine nucleosides

• Verfasst von: Buckup, Tiago [VerfasserIn]
• Verfasst von: Sarter, Christopher [VerfasserIn]
• Verfasst von: Volpp, Hans-Robert [VerfasserIn]
• Verfasst von: Jäschke, Andres [VerfasserIn]
• Verfasst von: Motzkus, Marcus [VerfasserIn]
• Titel: Ultrafast time-resolved spectroscopy of diarylethene-based photoswitchable deoxyuridine nucleosides
• Verf.angabe: Tiago Buckup, Christopher Sarter, Hans-Robert Volpp, Andres Jäschke, Marcus Motzkus
• E-Jahr: 2015
• Jahr: November 10, 2015
• Umfang: 5 S.
• Fussnoten: Gesehen am 20.10.2020
• Titel Quelle: Enthalten in: The journal of physical chemistry letters
• Ort Quelle: Washington, DC : ACS, 2010
• Jahr Quelle: 2015
• Band/Heft Quelle: 6(2015), 23, Seite 4717-4721
• ISSN Quelle: 1948-7185
• DOI: doi:10.1021/acs.jpclett.5b01949
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1736026313

Abstract

Photoswitches based on the diarylethene architecture have been attracting considerable attention for the investigation and control of a variety of biological processes. The reversible photoisomerization reaction between their open- and closed-ring forms can be selectively addressed by irradiation with light of two markedly different wavelengths. In this work, the dynamics of the photochromic ring-opening reaction of four novel diarylethene-based photoswitchable deoxyuridine nucleosides is investigated by femtosecond transient absorption. Upon photoexcitation with sub-20 fs pulses in the first absorption band (500 nm), all four photoswitches showed a fast ballistic excited-state deactivation within less than 500 fs toward the S1/S0 conical intersection. Transient data was globally analyzed, and a relaxation kinetic model with a branching between open and closed ring forms without any loss channels was derived. Ring-opening quantum yields, Φr-o, were found to strongly depend on the substituents (R), ranging from 0.64 (dUPSI: R = 2-naphthyl) to 0.30 (dUPSIV: R = 2-pyridyl).