Five years’ trajectories of functionality and pain in patients after hip or knee replacement and association with long-term patient survival

• Verfasst von: Repky, Stefan [VerfasserIn]
• Verfasst von: Büchele, Gisela [VerfasserIn]
• Verfasst von: Günther, Klaus-Peter [VerfasserIn]
• Verfasst von: Huch, Klaus [VerfasserIn]
• Verfasst von: Brenner, Hermann [VerfasserIn]
• Verfasst von: Stürmer, Til [VerfasserIn]
• Verfasst von: Beyersmann, Jan [VerfasserIn]
• Verfasst von: Brenner, Rolf E. [VerfasserIn]
• Verfasst von: Rothenbacher, Dietrich [VerfasserIn]
• Titel: Five years’ trajectories of functionality and pain in patients after hip or knee replacement and association with long-term patient survival
• Verf.angabe: Stefan Repky, Gisela Büchele, Klaus-Peter Günther, Klaus Huch, Hermann Brenner, Til Stürmer, Jan Beyersmann, Rolf E. Brenner, Dietrich Rothenbacher
• E-Jahr: 2020
• Jahr: 01 September 2020
• Umfang: 7 S.
• Fussnoten: Gesehen am 22.10.2020
• Titel Quelle: Enthalten in: Scientific reports
• Ort Quelle: [London] : Macmillan Publishers Limited, part of Springer Nature, 2011
• Jahr Quelle: 2020
• Band/Heft Quelle: 10(2020) Artikel-Nummer 14388, 7 Seiten
• ISSN Quelle: 2045-2322
• DOI: doi:10.1038/s41598-020-71277-3
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1736210874

Abstract

To describe the 5 years’ trajectories in functionality and pain of patients with hip or knee osteoarthritis and arthroplasty and analyze the association of these with long-term patients survival. Patients with OA receiving total hip or knee arthroplasty were recruited and completed two sets of standardized questionnaires for functionality and pain 6, 12, and 60 months postoperatively. Multivariate mixed models were conducted to assess trajectories over time and the resulting improvement per month during the last time period was included in a landmark-model to estimate adjusted hazard ratios for mortality. In total 809 patients with joint replacement were included (mean age 65.0 years, 62.2% female), 407 patients died (median follow-up 18.4 years). Both instruments of functionality and pain showed extensive improvement during the first 6 months. Baseline and change in functionality (both p < 0.001) and pain (p = 0.02) during the first 6 months were associated with mortality. Better values in functionality corresponded with improved survival whereas the association with the pain scores was inverse. In patients with hip and knee OA, an explicit improvement in function is seen within the first 6 months after arthroplasty. In addition, especially the functionality scores at baseline as well as their improvement showed an association with long-term patient survival.