| |  Online-Ressource |
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| Verfasst von: | Garbea, Andrea [VerfasserIn]  |
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| | Hildenbrand, Ralf [VerfasserIn] |
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| | Bleyl, Uwe [VerfasserIn] |
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| | Schadendorf, Dirk [VerfasserIn] |
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| | Goerdt, Sergij [VerfasserIn] |
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| Titel: | Cutaneous large B-cell lymphoma of the leg masquerading as a chronic venous ulcer |
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| Verf.angabe: | A. Garbea, E. Dippel, R. Hildenbrand, U. Bleyl, D. Schadendorf and S. Goerdt |
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| E-Jahr: | 2003 |
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| Jahr: | 12 February 2003 |
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| Jahr des Originals: | 2002 |
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| Umfang: | 4 S. |
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| Fussnoten: | Gesehen am 10.11.2020 ; Elektronische Reproduktion der Druckausgabe |
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| Titel Quelle: | Enthalten in: British journal of dermatology |
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| Ort Quelle: | Oxford : Oxford University Press, 1892 |
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| Jahr Quelle: | 2002 |
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| Band/Heft Quelle: | 146(2002), 1, Seite 144-147 |
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| ISSN Quelle: | 1365-2133 |
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| Abstract: | We report on a 74-year-old female patient with a primary cutaneous CD20+, diffuse large cell B-cell lymphoma of the lower leg resembling a chronic non-healing leg ulcer. There was no evidence of systemic involvement on computed tomography (CT) scans of the chest, abdomen and pelvis; a slightly enlarged lymph node in the right groin showed dermatopathic lymphadenopathy on histology and immunohistochemistry. Involvement of the bone marrow and peripheral blood was ruled out by punch biopsy and fluorescent activated cell sorter (FACS) analysis of the blood, respectively. Therapeutic anti-CD20 monoclonal antibody rituximab was given at 375 mg m−2 i.v. once weekly for 7 weeks, without adverse effects, resulting in a minor improvement in the centre of the ulcerated tumour. Unfortunately, the response was not maintained, and after 7 weeks of treatment the patient started to develop new tumour lesions at the border of the ulcer. Local radiotherapy was started and combined photon and electron beam irradiation induced complete remission of the B-cell lymphoma. |
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| DOI: | doi:10.1046/j.0007-0963.2001.04520.x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/https://doi.org/10.1046/j.0007-0963.2001.04520.x |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.0007-0963.2001.04520.x |
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| | DOI: https://doi.org/10.1046/j.0007-0963.2001.04520.x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | anti-CD20 monoclonal antibody therapy |
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| | cutaneous B-cell lymphoma |
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| | radiotherapy |
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| | rituximab |
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| | ulcers |
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| K10plus-PPN: | 1738324850 |
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| Verknüpfungen: | → Zeitschrift |
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Cutaneous large B-cell lymphoma of the leg masquerading as a chronic venous ulcer / Garbea, Andrea [VerfasserIn]; 12 February 2003 (Online-Ressource)
