Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Lehmann, Lorenz [VerfasserIn]  |
| Stanmore, David [VerfasserIn]  |
| Backs, Johannes [VerfasserIn]  |
Titel: | The role of endothelin-1 in the sympathetic nervous system in the heart |
Verf.angabe: | Lorenz H. Lehmann, David A. Stanmore, Johannes Backs |
E-Jahr: | 2014 |
Jahr: | 13 March 2014 |
Umfang: | 8 S. |
Fussnoten: | Gesehen am 10.11.2020 |
Titel Quelle: | Enthalten in: Life sciences |
Ort Quelle: | New York, NY [u.a.] : Elsevier Science, 1963 |
Jahr Quelle: | 2014 |
Band/Heft Quelle: | 118(2014), 2, Seite 165-172 |
ISSN Quelle: | 1879-0631 |
Abstract: | Endothelin-1 (ET1) is a peptide that was initially identified as a strong inductor of vascular contraction. In the last 25 years, there have been several biological processes identified in which ET1 seems to play a critical role. In particular, genetic studies have unveiled that ET1 is important for neuronal development, growth and function. Experimental studies identified ET1 as a regulator of the interaction between sympathetic neurons and cardiac myocytes. This might be of clinical importance since patients suffering from heart failure are characterized by disrupted norepinephrine homeostasis in the heart. This review summarizes the important findings on the role of ET1 for sympathetic neurons and norepinephrine homeostasis in the heart. |
DOI: | doi:10.1016/j.lfs.2014.03.005 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.lfs.2014.03.005 |
| DOI: https://doi.org/10.1016/j.lfs.2014.03.005 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Animals |
| Endothelin |
| Endothelin Receptor Antagonists |
| Endothelin-1 |
| Heart failure |
| Humans |
| Myocardium |
| Norepinephrine |
| Receptors, Endothelin |
| Signal Transduction |
| Sympathetic nervous system |
| Sympathetic Nervous System |
K10plus-PPN: | 1738328473 |
Verknüpfungen: | → Zeitschrift |
¬The¬ role of endothelin-1 in the sympathetic nervous system in the heart / Lehmann, Lorenz [VerfasserIn]; 13 March 2014 (Online-Ressource)
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