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Status: Bibliographieeintrag

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Verfasst von:Adam, Elisabeth [VerfasserIn]   i
 Fischer, Dania [VerfasserIn]   i
Titel:Plasma transfusion practice in adult surgical patients
Titelzusatz:systematic review of the literature
Verf.angabe:Elisabeth Hannah Adam, Dania Fischer
E-Jahr:2020
Jahr:September 18, 2020
Umfang:13 S.
Fussnoten:Gesehen am 19.11.2020
Titel Quelle:Enthalten in: Transfusion medicine and hemotherapy
Ort Quelle:Freiburg : Karger, 2003
Jahr Quelle:2020
Band/Heft Quelle:47(2020), 5, Seite 347-359
ISSN Quelle:1660-3818
Abstract:Background:Plasma transfusions are most commonly used therapeutically for bleeding or prophylactically in non-bleeding patients prior to invasive procedures or surgery. Although plasma transfusions generally seem to decline, plasma usage for indications that lack evidence of efficacy prevail.Summary:There is wide international, interinstitutional, and interindividual variance regarding the compliance with guidelines based on published references, supported by appropriate testing. There is furthermore a profound lack of evidence from randomized controlled trials comparing the effect of plasma transfusion with that of other therapeutic interventions for most indications, including massive bleeding. The expected benefit of a plasma transfusion needs to be balanced carefully against the associated risk of adverse events. In light of the heterogeneous nature of bleeding conditions and their rapid evolvement over time, fibrinogen and factor concentrate therapy, directed at specific phases of coagulation identified by alternative laboratory assays, may offer advantages over conventional blood product ratio-driven resuscitation. However, their outcome benefit has not been demonstrated in well-powered prospective trials. This systematic review will detail the current evidence base for plasma transfusion in adult surgical patients.
DOI:doi:10.1159/000511271
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1159/000511271
 DOI: https://doi.org/10.1159/000511271
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:acute lung injury
 blood-component therapy
 cardiac-surgery
 circulatory overload
 Coagulopathy management
 french lyophilized plasma
 Fresh frozen plasma
 fresh-frozen plasma
 Plasma transfusion
 Plasma usage
 prothrombin complex concentrate
 risk-factors
 solvent/detergent-treated plasma
 trauma-induced coagulopathy
K10plus-PPN:1739113446
Verknüpfungen:→ Zeitschrift

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