Topical treatment of tinea pedis using 6 % coriander oil in unguentum leniens

• Verfasst von: Beikert, Florian Christoph [VerfasserIn]
• Verfasst von: Anastasiadou, Z. [VerfasserIn]
• Verfasst von: Fritzen, Bernd [VerfasserIn]
• Verfasst von: Frank, Uwe [VerfasserIn]
• Verfasst von: Augustin, Matthias [VerfasserIn]
• Titel: Topical treatment of tinea pedis using 6 % coriander oil in unguentum leniens
• Titelzusatz: a randomized, controlled, comparative pilot study
• Verf.angabe: F.C. Beikert, Z. Anastasiadou, B. Fritzen, U. Frank, M. Augustin
• E-Jahr: 2013
• Jahr: March 1, 2013
• Umfang: 5 S.
• Fussnoten: Gesehen am 19.11.2020
• Titel Quelle: Enthalten in: Dermatology
• Ort Quelle: Basel : Karger, 1893
• Jahr Quelle: 2013
• Band/Heft Quelle: 226(2013), 1, Seite 47-51
• ISSN Quelle: 1421-9832
• DOI: doi:10.1159/000346641
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1739152751

Abstract

<b><i>Background:</i></b> The antifungal activity of coriander oil has already been demonstrated in vitro. <b><i>Objective:</i></b> Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. <b><i>Methods:</i></b> Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28. <b><i>Results:</i></b> 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good. <b><i>Conclusion:</i></b> Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.