Peripheral hypoarousal but not preparation-vigilance impairment endures in ADHD remission

• Verfasst von: James, Sarah-Naomi [VerfasserIn]
• Verfasst von: Cheung, Celeste H. M. [VerfasserIn]
• Verfasst von: Rommel, Anna-Sophie [VerfasserIn]
• Verfasst von: McLoughlin, Grainne [VerfasserIn]
• Verfasst von: Brandeis, Daniel [VerfasserIn]
• Verfasst von: Banaschewski, Tobias [VerfasserIn]
• Verfasst von: Asherson, Philip [VerfasserIn]
• Verfasst von: Kuntsi, Jonna [VerfasserIn]
• Titel: Peripheral hypoarousal but not preparation-vigilance impairment endures in ADHD remission
• Verf.angabe: Sarah-Naomi James, Celeste H.M. Cheung, Anna-Sophie Rommel, Grainne McLoughlin, Daniel Brandeis, Tobias Banaschewski, Philip Asherson, and Jonna Kuntsi
• E-Jahr: 2020
• Jahr: Nov 2020
• Umfang: 8 S.
• Fussnoten: Gesehen am 27.11.2020
• Titel Quelle: Enthalten in: Journal of attention disorders
• Ort Quelle: Thousand Oaks, Calif. : Sage, 1996
• Jahr Quelle: 2020
• Band/Heft Quelle: 24(2020), 13, Seite 1944-1951
• ISSN Quelle: 1557-1246
• DOI: doi:10.1177/1087054717698813
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: adhd
• Sach-SW: adolescents
• Sach-SW: adolescents/young adults
• Sach-SW: arousal
• Sach-SW: attention-deficit/hyperactivity disorder
• Sach-SW: deficit hyperactivity disorder
• Sach-SW: eeg
• Sach-SW: fmri
• Sach-SW: improvement
• Sach-SW: persistence
• Sach-SW: prevalence
• Sach-SW: remission
• Sach-SW: skin-conductance
• K10plus-PPN: 1741389542

Abstract

Objective:This study investigates whether impairments associated with persistent ADHD-impaired attention allocation (P3 amplitude), peripheral hypoarousal (skin conductance level [SCL]), and adjustment in preparatory state (contingent negative variation [CNV])-reflect enduring deficits unrelated to ADHD outcome or are markers of ADHD remission.Method:Young people with childhood ADHD (73 persisters and 18 remitters) and 144 controls were compared on neurophysiological measures during two conditions (baseline and fast-incentive) of a four-choice reaction time task.Results:ADHD remitters differed from persisters, and were indistinguishable from controls, on baseline P3 amplitude and fast-incentive CNV amplitude (p <= .05). ADHD remitters differed from controls (p <= .01), and were indistinguishable from persisters (p> .05), on baseline SCL.Conclusion:Preparation-vigilance measures were markers of ADHD remission, confirming previous findings with other measures. Yet, SCL-measured peripheral hypoarousal emerges as an enduring deficit unrelated to ADHD improvement. Future studies should explore potential compensatory mechanisms that enable efficient preparation-vigilance processes in ADHD remitters.