Hair cortisol moderates the association between obstetric complications and child wellbeing

• Verfasst von: Fuchs, Anna [VerfasserIn]
• Verfasst von: Dittrich, Katja [VerfasserIn]
• Verfasst von: Neukel, Corinne [VerfasserIn]
• Verfasst von: Winter, Sibylle [VerfasserIn]
• Verfasst von: Zietlow, Anna-Lena [VerfasserIn]
• Verfasst von: Kluczniok, Dorothea [VerfasserIn]
• Verfasst von: Herpertz, Sabine [VerfasserIn]
• Verfasst von: Hindi Attar, Catherine [VerfasserIn]
• Verfasst von: Möhler, Eva [VerfasserIn]
• Verfasst von: Fydrich, Thomas [VerfasserIn]
• Verfasst von: Bermpohl, Felix [VerfasserIn]
• Verfasst von: Kaess, Michael [VerfasserIn]
• Verfasst von: Resch, Franz [VerfasserIn]
• Verfasst von: Bödeker, Katja [VerfasserIn]
• Titel: Hair cortisol moderates the association between obstetric complications and child wellbeing
• Verf.angabe: Anna Fuchs, Katja Dittrich, Corinne Neukel, Sibylle Winter, Anna-Lena Zietlow, Dorothea Kluczniok, Sabine C. Herpertz, Catherine Hindi Attar, Eva Möhler, Thomas Fydrich, Felix Bermpohl, Michael Kaess, Franz Resch, Katja Bödeker
• E-Jahr: 2020
• Jahr: 18 August 2020
• Umfang: 8 S.
• Fussnoten: Gesehen am 17.12.2020
• Titel Quelle: Enthalten in: Psychoneuroendocrinology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1975
• Jahr Quelle: 2020
• Band/Heft Quelle: 121(2020) Artikel-Nummer 104845, 8 Seiten
• ISSN Quelle: 1873-3360
• DOI: doi:10.1016/j.psyneuen.2020.104845
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Behavior problems
• Sach-SW: Children
• Sach-SW: Hair cortisol
• Sach-SW: Internalizing/Externalizing
• Sach-SW: Obstetric complications
• Sach-SW: Quality of life
• K10plus-PPN: 1743100825

Abstract

Obstetric complications (OC) may have implications for later health outcomes. However, there is a lack of research examining the association between OC and behavior problems or quality of life (HRQoL). We aimed to close this gap and further investigate functioning of the hypothalamus-pituitary-adrenal (HPA)-axis as a potential physiological vulnerability moderating the association between OC and behavior problems and HRQoL. We investigated 232 mothers and their five to 12-year-old children. Presence of OC during the pre-, peri-, and postnatal phases was determined by interviewing mothers. Children’s behavior problems (CBCL, TRF) and HRQoL (Kidscreen rated by mothers and children) were assessed. Children gave 3 cm strands of hair for analysis of hair cortisol (HC). Structural equation modeling analyses with a latent variable of child outcome (“distress”), OC as predictor and HC as a potential moderator were conducted. OC significantly predicted distress (β = .33, p < .01). The model showed a good fit to the data: χ2(14)=15.66, p < .33, CFI=.99, TLI=.99, RMSEA=.02, 90 %CI [.00, .06], SRMR=.04. In addition, HC moderated the association between OC and distress (β=-.32, p < .01). The moderation model also showed a good fit: χ2(14) =7.13, p = .93, CFI=1.00, TLI=1.06, RMSEA=.00, 90 %CI [.00, .02], SRMR=.03. Results indicated that the association between OC and distress was significant only when children had low HC-levels. This was also the case for both externalizing and internalizing behavior problems. Our results underline the notion of OC as a risk factor for child behavior problems and wellbeing and point to an important role of the children’s physiological set-up such as HPA-functioning.