| |  Online-Ressource |
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| Verfasst von: | Mehrabi, Arianeb [VerfasserIn]  |
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| | Golriz, Mohammad [VerfasserIn] |
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| | Adili-Aghdam, Fatemeh [VerfasserIn] |
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| | Hafezi, Mohammadreza [VerfasserIn] |
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| | Ashrafi, Maryam [VerfasserIn] |
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| | Morath, Christian [VerfasserIn] |
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| | Zeier, Martin [VerfasserIn] |
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| | Hackert, Thilo [VerfasserIn] |
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| | Schemmer, Peter [VerfasserIn] |
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| Titel: | Expanding the indications of pancreas transplantation alone |
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| Verf.angabe: | Arianeb Mehrabi, Mohammad Golriz, Fatemeh Adili-Aghdam, Mohammadreza Hafezi, Maryam Ashrafi, Christian Morath, Martin Zeier, Thilo Hackert, and Peter Schemmer |
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| Jahr: | 2014 |
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| Umfang: | 4 S. |
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| Fussnoten: | Gesehen am 22.12.2020 |
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| Titel Quelle: | Enthalten in: Pancreas |
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| Ort Quelle: | Philadelphia, Pa. : Lippincott Williams & Wilkins, 1986 |
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| Jahr Quelle: | 2014 |
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| Band/Heft Quelle: | 43(2014), 8, Seite 1190-1193 |
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| ISSN Quelle: | 1536-4828 |
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| Abstract: | OBJECTIVES: Total pancreatectomy (TP) is associated with postoperative endocrine and exocrine insufficiency. Especially, insulin therapy reduces quality of life and may lead to long-term complications. We review the literature with regard to the potential option of pancreas transplantation alone (PTA) after TP in patients with chronic pancreatitis or benign tumors. - METHODS: A MEDLINE search (1958-2013) using the terminologies pancreas transplantation, pancreas transplantation alone, total pancreatectomy, morbidity, mortality, insulin therapy, and quality of life was performed. In addition, the current book and congress publications were reviewed. - RESULTS: Total pancreatectomy after benign and borderline tumors as well as chronic pancreatitis is continuously increasing. Despite improvement of exogenous insulin therapy, more than 50% of these patients experience severe glucose control problems, which cause up to 50% long-term mortality. Pancreas transplantation alone can cure both endocrine and exocrine insufficiency and reduce the associated risks. The 3-year graft and patient survival rates after PTA are up to 73% and 100%, respectively. - CONCLUSIONS: Pancreas transplantation alone after TP in patients with pancreatitis or benign tumors improves the recipient's quality of life and reduces long-term mortality. Considering the amount of available organs and potential candidates, PTA can be a treatment option for patients after TP with chronic pancreatitis or benign tumors. |
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| DOI: | doi:10.1097/MPA.0000000000000181 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1097/MPA.0000000000000181 |
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| | DOI: https://doi.org/10.1097/MPA.0000000000000181 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Cost-Benefit Analysis |
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| | Diabetes Mellitus, Type 1 |
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| | Exocrine Pancreatic Insufficiency |
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| | Global Health |
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| | Graft Survival |
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| | Humans |
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| | Immunosuppressive Agents |
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| | Insulin |
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| | Islets of Langerhans Transplantation |
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| | Pancreas Transplantation |
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| | Pancreatectomy |
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| | Pancreatic Neoplasms |
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| | Pancreatitis, Chronic |
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| | Postoperative Complications |
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| | Quality of Life |
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| | Tissue and Organ Procurement |
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| | Treatment Outcome |
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| | Waiting Lists |
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| K10plus-PPN: | 1743510802 |
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| Verknüpfungen: | → Zeitschrift |
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Expanding the indications of pancreas transplantation alone / Mehrabi, Arianeb [VerfasserIn]; 2014 (Online-Ressource)
