Esperanto for histones

• Verfasst von: Earnshaw, William C. [VerfasserIn]
• Verfasst von: Erhardt, Sylvia [VerfasserIn]
• Verfasst von: Cleveland, D. W. [VerfasserIn]
• Titel: Esperanto for histones
• Titelzusatz: CENP-A, not CenH3, is the centromeric histone H3 variant
• Verf.angabe: W.C. Earnshaw, S. Erhardt, und weitere 55
• E-Jahr: 2013
• Jahr: 12 April 2013
• Umfang: 6 S.
• Fussnoten: Gesehen am 07.01.2021
• Titel Quelle: Enthalten in: Chromosome research
• Ort Quelle: Dordrecht : Springer Science + Business Media B.V., 1993
• Jahr Quelle: 2013
• Band/Heft Quelle: 21(2013), 2, Seite 101-106
• ISSN Quelle: 1573-6849
• DOI: doi:10.1007/s10577-013-9347-y
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1744187347

Abstract

The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.