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Verfasst von:Basu, Biswanath [VerfasserIn]   i
 Erdmann, Stella [VerfasserIn]   i
 Sander, Anja [VerfasserIn]   i
 Mahapatra, T. K. S. [VerfasserIn]   i
 Schaefer, Franz [VerfasserIn]   i
Titel:Randomized clinical trial to compare efficacy and safety of repeated courses of rituximab to single-course rituximab followed by maintenance mycophenolate-mofetil in children with steroid dependent nephrotic syndrome
Verf.angabe:Biswanath Basu, Stella Preussler, Anja Sander, T.K.S. Mahapatra and Franz Schaefer
E-Jahr:2020
Jahr:30 November 2020
Umfang:11 S.
Fussnoten:Gesehen am 08.01.2021
Titel Quelle:Enthalten in: BMC nephrology
Ort Quelle:London : BioMed Central, 2000
Jahr Quelle:2020
Band/Heft Quelle:21(2020), Artikel-ID 520, Seite 1-11
ISSN Quelle:1471-2369
Abstract:Approximately 30% of children with idiopathic nephrotic syndrome develop a complicated course with frequent relapses or steroid dependency. Rituximab, a B cell depleting monoclonal antibody, is a safe and effective alternative to steroids or other immunosuppressants for achieving and maintaining remission in this population at short term. Despite the good initial response relapses inevitably occur after regeneration of B lymphocytes, necessitating either repeat courses of rituximab or addition of another steroid-sparing immunosuppressant.
DOI:doi:10.1186/s12882-020-02153-5
URL:kostenfrei: Volltext: https://doi.org/10.1186/s12882-020-02153-5
 kostenfrei: Volltext: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-020-02153-5
 DOI: https://doi.org/10.1186/s12882-020-02153-5
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Childhood nephrotic syndrome
 Mycophenolate-Mofetil
 Rituximab
 Steroid dependent nephrotic syndrome
K10plus-PPN:1744215634
Verknüpfungen:→ Zeitschrift
 
 
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