| Online-Ressource |
Verfasst von: | Vollherbst, Dominik [VerfasserIn]  |
| Gebhart, Philipp [VerfasserIn]  |
| Kargus, Steffen [VerfasserIn]  |
| Burger, Astrid [VerfasserIn]  |
| Kühle, Reinald [VerfasserIn]  |
| Günther, Patrick [VerfasserIn]  |
| Hoffmann, Jürgen [VerfasserIn]  |
| Bendszus, Martin [VerfasserIn]  |
| Möhlenbruch, Markus Alfred [VerfasserIn]  |
Titel: | Image-guided percutaneous sclerotherapy of venous malformations of the head and neck |
Titelzusatz: | clinical and MR-based volumetric mid-term outcome |
Verf.angabe: | Dominik F. Vollherbst, Philipp Gebhart, Steffen Kargus, Astrid Burger, Reinald Kühle, Patrick Günther, Jürgen Hoffmann, Martin Bendszus, Markus A. Möhlenbruch |
E-Jahr: | 2020 |
Jahr: | October29, 2020 |
Umfang: | 12 S. |
Fussnoten: | Gesehen am 25.01.2021 |
Titel Quelle: | Enthalten in: PLOS ONE |
Ort Quelle: | San Francisco, California, US : PLOS, 2006 |
Jahr Quelle: | 2020 |
Band/Heft Quelle: | 15(2020,10) Artikel-Nummer e0241347, 12 Seiten |
ISSN Quelle: | 1932-6203 |
Abstract: | Objective To report the clinical and MRI-based volumetric mid-term outcome after image guided percutaneous sclerotherapy (PS) of venous malformations (VM) of the head and neck. Methods A retrospective analysis of a prospectively maintained database was performed, including patients with VM of the head and neck who were treated with PS. Only patients with available pre- and post-interventional MRI were included into this study. Clinical outcome, which was subjectively assessed by the patients, their parents (for paediatric patients) and/or the physicians, was categorized as worse, unchanged, minor or major improvement. Radiological outcome, determined by MRI-based volumetric measurements, was categorized as worse (>10% increase), unchanged (≤10% increase to <10% decrease), minor (≥10% to <25% decrease), intermediate (≥25% to <50% decrease) or major improvement (≥50% decrease). Results Twenty-seven patients were treated in 51 treatment sessions. After a mean follow-up of 31 months, clinical outcome was worse for 7.4%, unchanged for 3.7% of the patients, while there was minor and major improvement for 7.4% and 81.5%, respectively. In the volumetric imaging analysis 7.4% of the VMs were worse and 14.8% were unchanged. Minor improvement was observed in 22.2%, intermediate improvement in 44.4% and major improvement in 11.1%. The rate of permanent complications was 3.7%. Conclusion PS can be an effective therapy to treat the symptoms of patients with VMs of the head and neck and to downsize the VMs. MRI-based volumetry can be used to objectively follow the change in size of the VMs after PS. Relief of symptoms frequently does not require substantial volume reduction. |
DOI: | doi:10.1371/journal.pone.0241347 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1371/journal.pone.0241347 |
| Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241347 |
| DOI: https://doi.org/10.1371/journal.pone.0241347 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Adverse events |
| Ethanol |
| Foams |
| Head |
| Lesions |
| Magnetic resonance imaging |
| Neck |
| Pain |
K10plus-PPN: | 1745559957 |
Verknüpfungen: | → Zeitschrift |
Image-guided percutaneous sclerotherapy of venous malformations of the head and neck / Vollherbst, Dominik [VerfasserIn]; October29, 2020 (Online-Ressource)