Image-guided percutaneous sclerotherapy of venous malformations of the head and neck

• Verfasst von: Vollherbst, Dominik [VerfasserIn]
• Verfasst von: Gebhart, Philipp [VerfasserIn]
• Verfasst von: Kargus, Steffen [VerfasserIn]
• Verfasst von: Burger, Astrid [VerfasserIn]
• Verfasst von: Kühle, Reinald [VerfasserIn]
• Verfasst von: Günther, Patrick [VerfasserIn]
• Verfasst von: Hoffmann, Jürgen [VerfasserIn]
• Verfasst von: Bendszus, Martin [VerfasserIn]
• Verfasst von: Möhlenbruch, Markus Alfred [VerfasserIn]
• Titel: Image-guided percutaneous sclerotherapy of venous malformations of the head and neck
• Titelzusatz: clinical and MR-based volumetric mid-term outcome
• Verf.angabe: Dominik F. Vollherbst, Philipp Gebhart, Steffen Kargus, Astrid Burger, Reinald Kühle, Patrick Günther, Jürgen Hoffmann, Martin Bendszus, Markus A. Möhlenbruch
• E-Jahr: 2020
• Jahr: October29, 2020
• Umfang: 12 S.
• Fussnoten: Gesehen am 25.01.2021
• Titel Quelle: Enthalten in: PLOS ONE
• Ort Quelle: San Francisco, California, US : PLOS, 2006
• Jahr Quelle: 2020
• Band/Heft Quelle: 15(2020,10) Artikel-Nummer e0241347, 12 Seiten
• ISSN Quelle: 1932-6203
• DOI: doi:10.1371/journal.pone.0241347
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Adverse events
• Sach-SW: Ethanol
• Sach-SW: Foams
• Sach-SW: Head
• Sach-SW: Lesions
• Sach-SW: Magnetic resonance imaging
• Sach-SW: Neck
• Sach-SW: Pain
• K10plus-PPN: 1745559957

Abstract

Objective To report the clinical and MRI-based volumetric mid-term outcome after image guided percutaneous sclerotherapy (PS) of venous malformations (VM) of the head and neck. Methods A retrospective analysis of a prospectively maintained database was performed, including patients with VM of the head and neck who were treated with PS. Only patients with available pre- and post-interventional MRI were included into this study. Clinical outcome, which was subjectively assessed by the patients, their parents (for paediatric patients) and/or the physicians, was categorized as worse, unchanged, minor or major improvement. Radiological outcome, determined by MRI-based volumetric measurements, was categorized as worse (>10% increase), unchanged (≤10% increase to <10% decrease), minor (≥10% to <25% decrease), intermediate (≥25% to <50% decrease) or major improvement (≥50% decrease). Results Twenty-seven patients were treated in 51 treatment sessions. After a mean follow-up of 31 months, clinical outcome was worse for 7.4%, unchanged for 3.7% of the patients, while there was minor and major improvement for 7.4% and 81.5%, respectively. In the volumetric imaging analysis 7.4% of the VMs were worse and 14.8% were unchanged. Minor improvement was observed in 22.2%, intermediate improvement in 44.4% and major improvement in 11.1%. The rate of permanent complications was 3.7%. Conclusion PS can be an effective therapy to treat the symptoms of patients with VMs of the head and neck and to downsize the VMs. MRI-based volumetry can be used to objectively follow the change in size of the VMs after PS. Relief of symptoms frequently does not require substantial volume reduction.