| |  Online-Ressource |
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| Verfasst von: | Moratin, Julius [VerfasserIn]  |
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| | Horn, Dominik [VerfasserIn] |
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| | Semmelmayer, Karl [VerfasserIn] |
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| | Ristow, Oliver [VerfasserIn] |
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| | Flechtenmacher, Christa [VerfasserIn] |
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| | Engel, Michael [VerfasserIn] |
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| | Hoffmann, Jürgen [VerfasserIn] |
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| | Freier, Kolja [VerfasserIn] |
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| | Freudlsperger, Christian [VerfasserIn] |
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| Titel: | Squamous cell carcinoma of the mandible - Patterns of metastasis and disease recurrence in dependence of localization and therapy |
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| Verf.angabe: | Julius Moratin, Dominik Horn, Karl Metzger, Oliver Ristow, Christa Flechtenmacher, Michael Engel, Jürgen Hoffmann, Kolja Freier, Christian Freudlsperger |
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| E-Jahr: | 2020 |
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| Jahr: | 1 November 2020 |
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| Umfang: | 6 S. |
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| Fussnoten: | Gesehen am 26.01.2021 |
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| Titel Quelle: | Enthalten in: Journal of cranio-maxillofacial surgery |
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| Ort Quelle: | Oxford [u.a.] : Elsevier, 1987 |
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| Jahr Quelle: | 2020 |
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| Band/Heft Quelle: | 48(2020), 12, Seite 1158-1163 |
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| ISSN Quelle: | 1878-4119 |
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| Abstract: | Introduction - Oral squamous cell carcinomas exhibit distinct patterns of disease progression, depending on their localisation. This study aimed to evaluate clinicopathological data in patients with tumors of the mandibular alveolar process, to facilitate risk assessment and therapy planning. - Materials and methods - A retrospective cohort study was designed including patients with squamous cell carcinoma of the mandibular gingiva. Clinical and pathological data were collected to determine the rate of cervical metastases and clinical outcomes depending on tumor stage, localization (anterior, intermediate and posterior) and the extent of tumor resection. - Results - 120 patients were included in the analysis. Rate of metastases was 42.6%. Tumors of the anterior part of the mandible exhibited significantly higher rates of bilateral metastases (anterior: 85.7%, intermediate: 15.8%, posterior: 4%, p < 0.001) and local recurrence (anterior: 25%, intermediate: 16.3%, posterior: 5.5%, p = 0.03) compared to posterior malignancies. - Conclusion - Tumors of the anterior segment of the mandible are characterized by high rates of metastases and local recurrence. Therefore, we propose radical segmental resection and bilateral neck dissection in those patients. |
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| DOI: | doi:10.1016/j.jcms.2020.10.006 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.jcms.2020.10.006 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S1010518220302341 |
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| | DOI: https://doi.org/10.1016/j.jcms.2020.10.006 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Mandible |
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| | Metastasis |
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| | Neck dissection |
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| | OSCC |
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| | Survival |
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| K10plus-PPN: | 174567540X |
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| Verknüpfungen: | → Zeitschrift |
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Squamous cell carcinoma of the mandible - Patterns of metastasis and disease recurrence in dependence of localization and therapy / Moratin, Julius [VerfasserIn]; 1 November 2020 (Online-Ressource)
