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Verfasst von:Wacker, Christian [VerfasserIn]   i
 Bock, Michael [VerfasserIn]   i
 Bauer, Wolfgang Rudolf [VerfasserIn]   i
 Kaick, Gerhard van [VerfasserIn]   i
 Pfleger, Stefan [VerfasserIn]   i
 Schad, Lothar R. [VerfasserIn]   i
Titel:BOLD-MRI in ten patients with coronary artery disease
Titelzusatz:evidence for imaging of capillary recruitment in myocardium supplied by the stenotic artery
Verf.angabe:Christian M. Wacker, Michael Bock, Andreas W. Hartlep, Wolfgang R. Bauer, Gerhard van Kaick, Stefan Pfleger, Georg Ertl, Lothar R. Schad
E-Jahr:1999
Jahr:March 1999
Umfang:7 S.
Fussnoten:Gesehen am 17.02.2021
Titel Quelle:Enthalten in: Magnetic resonance materials in physics, biology and medicine
Ort Quelle:Heidelberg : Springer, 1993
Jahr Quelle:1999
Band/Heft Quelle:8(1999), Seite 48-54
ISSN Quelle:1352-8661
Abstract:Changes of myocardial oxygenation can be studied by measurements of the apparent transverse relaxation timeT 2 * , which is correlated with the oxygenation state of hemoglobin. In this study, ten patients with coronary artery disease (CAD) underwent blood oxygenation level dependent (BOLD)T 2 * measurements using a segmented gradient echo pulse sequence with ten echoes.T 2 * measurements were performed in a single short-axis slice of the heart at rest and under pharmacological stress with dipyridamole (DIP), which increases myocardial blood flow. For comparison, all patients underwent X-ray angiography and stress-echocardiography within 4 days after the MR exam. In one patient, MR examination was repeated 10 weeks after percutaneous transluminal coronary angioplasty (PTA). In the differentialT 2 * maps, expected ischemic areas of myocardium were identified in six patients. In these regions,T 2 * values (30±8 ms) were significantly reduced when compared to the remaining myocardium (48±9 ms,P<0.01). In four patients, the myocardial region of interest could not be assessed owing to severe susceptibility artifacts in the ischemic region. The success of the PTA treatment could be visualized from a more homogeneous DIP induced increase inT 2 * within the ischemic myocardium (from 26±1 to 29±1 ms before PTA versus 26±1 to 31±4 ms after PTA,P<0.001.
DOI:doi:10.1007/BF02590635
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1007/BF02590635
 Volltext: https://link.springer.com/article/10.1007/BF02590635
 DOI: https://doi.org/10.1007/BF02590635
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:174849161X
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