| Online-Ressource |
Verfasst von: | Wacker, Christian [VerfasserIn]  |
| Bock, Michael [VerfasserIn]  |
| Bauer, Wolfgang Rudolf [VerfasserIn]  |
| Kaick, Gerhard van [VerfasserIn]  |
| Pfleger, Stefan [VerfasserIn]  |
| Schad, Lothar R. [VerfasserIn]  |
Titel: | BOLD-MRI in ten patients with coronary artery disease |
Titelzusatz: | evidence for imaging of capillary recruitment in myocardium supplied by the stenotic artery |
Verf.angabe: | Christian M. Wacker, Michael Bock, Andreas W. Hartlep, Wolfgang R. Bauer, Gerhard van Kaick, Stefan Pfleger, Georg Ertl, Lothar R. Schad |
E-Jahr: | 1999 |
Jahr: | March 1999 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 17.02.2021 |
Titel Quelle: | Enthalten in: Magnetic resonance materials in physics, biology and medicine |
Ort Quelle: | Heidelberg : Springer, 1993 |
Jahr Quelle: | 1999 |
Band/Heft Quelle: | 8(1999), Seite 48-54 |
ISSN Quelle: | 1352-8661 |
Abstract: | Changes of myocardial oxygenation can be studied by measurements of the apparent transverse relaxation timeT 2 * , which is correlated with the oxygenation state of hemoglobin. In this study, ten patients with coronary artery disease (CAD) underwent blood oxygenation level dependent (BOLD)T 2 * measurements using a segmented gradient echo pulse sequence with ten echoes.T 2 * measurements were performed in a single short-axis slice of the heart at rest and under pharmacological stress with dipyridamole (DIP), which increases myocardial blood flow. For comparison, all patients underwent X-ray angiography and stress-echocardiography within 4 days after the MR exam. In one patient, MR examination was repeated 10 weeks after percutaneous transluminal coronary angioplasty (PTA). In the differentialT 2 * maps, expected ischemic areas of myocardium were identified in six patients. In these regions,T 2 * values (30±8 ms) were significantly reduced when compared to the remaining myocardium (48±9 ms,P<0.01). In four patients, the myocardial region of interest could not be assessed owing to severe susceptibility artifacts in the ischemic region. The success of the PTA treatment could be visualized from a more homogeneous DIP induced increase inT 2 * within the ischemic myocardium (from 26±1 to 29±1 ms before PTA versus 26±1 to 31±4 ms after PTA,P<0.001. |
DOI: | doi:10.1007/BF02590635 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/BF02590635 |
| Volltext: https://link.springer.com/article/10.1007/BF02590635 |
| DOI: https://doi.org/10.1007/BF02590635 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 174849161X |
Verknüpfungen: | → Zeitschrift |
BOLD-MRI in ten patients with coronary artery disease / Wacker, Christian [VerfasserIn]; March 1999 (Online-Ressource)