Adapters in lymphocyte signalling

• Verfasst von: Leo, Albrecht [VerfasserIn]
• Verfasst von: Schraven, Burkhart [VerfasserIn]
• Titel: Adapters in lymphocyte signalling
• Verf.angabe: Albrecht Leo, Burkhart Schraven
• Jahr: 2001
• Umfang: 10 S.
• Fussnoten: Gesehen am 19.02.2021
• Titel Quelle: Enthalten in: Current opinion in immunology
• Ort Quelle: Philadelphia, Pa. : Current Science, 1988
• Jahr Quelle: 2001
• Band/Heft Quelle: 13(2001), 3, Seite 307-316
• ISSN Quelle: 1879-0372
• DOI: doi:10.1016/s0952-7915(00)00220-x
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Animals
• Sach-SW: B-Lymphocytes
• Sach-SW: Carrier Proteins
• Sach-SW: Cell Communication
• Sach-SW: Humans
• Sach-SW: Lymphocyte Activation
• Sach-SW: Phosphoproteins
• Sach-SW: Signal Transduction
• Sach-SW: T-Lymphocytes
• K10plus-PPN: 1748664948

Abstract

Adapter proteins are well recognised as important molecular switches connecting immunoreceptors with intracellular signalling pathways. However, recent data suggest that homeostasis within the lymphatic system also depends on the coordinated activities of negative regulatory adapter proteins. These prevent activation of lymphocytes in the absence of externally applied signals and regulate termination/limitation of ongoing immune responses via different mechanisms.