Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Falckenhayn, Cassandra [VerfasserIn]   i
 Boerjan, Bart [VerfasserIn]   i
 Raddatz, Günter [VerfasserIn]   i
 Frohme, Marcus [VerfasserIn]   i
 Schoofs, Liliane [VerfasserIn]   i
 Lyko, Frank [VerfasserIn]   i
Titel:Characterization of genome methylation patterns in the desert locust Schistocerca gregaria
Verf.angabe:Cassandra Falckenhayn, Bart Boerjan, Günter Raddatz, Marcus Frohme, Liliane Schoofs and Frank Lyko
E-Jahr:2013
Jahr:15 April 2013
Umfang:7 S.
Fussnoten:Gesehen am 25.02.2021
Titel Quelle:Enthalten in: The journal of experimental biology
Ort Quelle:Cambridge : Company of Biologists, 1923
Jahr Quelle:2013
Band/Heft Quelle:216(2013), 8, Seite 1423-1429
ISSN Quelle:1477-9145
Abstract:Skip to Next Section - DNA methylation is a widely conserved epigenetic modification. The analysis of genome-scale DNA methylation patterns in various organisms suggests that major features of animal methylomes are widely conserved. However, based on the variation of DNA methyltransferase genes in invertebrates, it has also been proposed that DNA methylation could provide a molecular mechanism for ecological adaptation. We have now analyzed the methylome of the desert locust, Schistocerca gregaria, which represents an organism with a high degree of phenotypic plasticity. Using genome-scale bisulfite sequencing, we show here that the S. gregaria methylome is characterized by CpG- and exon-specific methylation and thus shares two major features with other animal methylomes. In contrast to other invertebrates, however, overall methylation levels were substantially higher and a significant fraction of transposons was methylated. Additionally, genic sequences were densely methylated in a pronounced bimodal pattern, suggesting a role for DNA methylation in the regulation of locust gene expression. Our results thus uncover a unique pattern of genome methylation in locusts and provide an important foundation for investigating the role of DNA methylation in locust phase polyphenism.
DOI:doi:10.1242/jeb.080754
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1242/jeb.080754
 Volltext: https://jeb.biologists.org/content/216/8/1423
 DOI: https://doi.org/10.1242/jeb.080754
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1749471094
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68704079   QR-Code
zum Seitenanfang