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Verfasst von:Kruse, Friedrich E. [VerfasserIn]   i
 Rohrschneider, Klaus [VerfasserIn]   i
 Völcker, Hans Eberhard [VerfasserIn]   i
Titel:Multilayer amniotic membrane transplantation for reconstruction of deep corneal ulcers
Verf.angabe:Friedrich E Kruse, Klaus Rohrschneider, Hans E Völcker
Jahr:1999
Umfang:8 S.
Fussnoten:Available online 25 August 2003 ; Gesehen am 03.03.2021
Titel Quelle:Enthalten in: Ophthalmology
Ort Quelle:Amsterdam [u.a.] : Elsevier, 1978
Jahr Quelle:1999
Band/Heft Quelle:106(1999), 8, Seite 1504-1511
ISSN Quelle:1549-4713
Abstract:Purpose - To evaluate the efficacy of multilayer amniotic membrane transplantation for reconstruction of corneal epithelium and stroma in the context of deep corneal ulcers. - Design - Prospective, noncomparative, interventional case series. - Participants - Eleven consecutive patients with deep corneal ulcers refractory to conventional treatment; six patients had herpetic keratitis and five had other forms of neurotrophic keratitis. - Intervention - Multilayer amniotic membrane transplantation with kryopreserved human amniotic membrane. - Main outcome measures - Integrity of corneal epithelium and stroma, opacification, and appearance of grafted membrane during 12 months follow-up. - Results - Amniotic membrane transplantation markedly reduced ocular inflammation in all patients. Epithelium healed above all corneal ulcers within 4 weeks and remained stable in 9 of 11 patients for 1 year. Two patients with recurrent epithelial defect suffered from severe neurotrophic keratitis. Following transplantation the amniotic membranes gradually dissolved over a period of 12 months, but stromal thickness remained stable. - Conclusion - Amniotic membrane transplantation allows corneal surface reconstruction in patients with persistent epithelial defects. The multilayer technique is useful for treating deep corneal ulcers and even descemetoceles. Because the procedure results in stability of the ocular surface over a period of more than 12 months in most patients, it may be considered an alternative to conventional surgical techniques for ocular surface reconstruction.
DOI:doi:10.1016/S0161-6420(99)90444-X
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/S0161-6420(99)90444-X
 Volltext: https://www.sciencedirect.com/science/article/pii/S016164209990444X
 DOI: https://doi.org/10.1016/S0161-6420(99)90444-X
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1750234254
Verknüpfungen:→ Zeitschrift

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